If both parents are heterozygous for Huntington's disease, what is the likelihood that their offspring will have Huntington's disease?

A) 100%
B) 75%
C) 50%
D) 25%
E) 0%

Question

If both parents are heterozygous for Huntington's disease, what is the likelihood that their offspring will have Huntington's disease?A) 100%B) 75%C) 50%D) 25%E) 0%

Alessandro Bravo · Accepted Answer

Final Answer : B, Explanation :  Huntington's disease is inherited in an autosomal dominant manner. If both parents are heterozygous (Aa), the offspring have a 75% chance of inheriting at least one dominant allele (AA or Aa) and thus having the disease. The possible genotypes are AA, Aa, Aa, and aa, with only the aa genotype not resulting in the disease.

If both parents are heterozygous for Huntington's disease, what is the likelihood that their offspring will have Huntington's disease?

A) 100%
B) 75%
C) 50%
D) 25%
E) 0%

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