A) Some conditions are due to nuclear genes.
B) Many of the conditions are due to translation errors.
C) There are different kinds and numbers of mutations per gene.
D) Each parent may contribute different mutations.
E) Exon shuffling allows different polypeptides to form.
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A) homozygous
B) heteroplasmic
C) homoplasmic
D) variegated
E) uniparental
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A) Heteroplastic cells can give rise to homoplastic cells.
B) Large mitochondria in oocytes can divide into many smaller mitochondria, and smaller mitochondria can fuse.
C) Specific tissue types replicate organelle DNA far more frequently than they do nuclear DNA.
D) Mutant mitochondria replicate at different frequencies than do wild type.
E) Haploid organelle genomes can replicate to form diploid or polyploidy genomes.
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A) Interference with translation slows protein formation and therefore maintenance of mutation-bearing organelles.
B) Having homoplastic organelles would no doubt be lethal due to curtailed translation.
C) Lysine is required in translation of every one of the mitochondrial genes.
D) Mutations of this gene affect individuals before birth.
E) Mutations of this gene are inherited as dominant characteristics.
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A) Sequence the mtDNA of the twitchy mother.
B) Breed twitchy male progeny with normal females to show no paternal inheritance.
C) Breed twitchy female with twitchy male F1 mice to verify there is maternal inheritance.
D) Backcross twitchy female offspring with normal fathers.
E) Sequence the mtDNA of the twitchy male offspring.
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