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Why is the formation of glucose 1-phosphate advantageous?

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It is advantageous because the...

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The protein ____________ is the δ subunit of phosphorylase kinase.


A) reducing
B) ɑ-1,6-glycosidic
C) phosphorylase kinase
D) ɑ-1,4-glycoside
E) nonreducing
F) phosphorylase a
G) glucose 6-phosphatase
H) UTP-glucose
I) calmodulin
J) phosphorolysis
K) epinephrine
L) glucagon

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____________: Most of the glucose residues in glycogen are linked by this type of bond.


A) reducing
B) ɑ-1,6-glycosidic
C) phosphorylase kinase
D) ɑ-1,4-glycoside
E) nonreducing
F) phosphorylase a
G) glucose 6-phosphatase
H) UTP-glucose
I) calmodulin
J) phosphorolysis
K) epinephrine
L) glucagon

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One mechanism for turning off glycogen degradation involves the removal of a phosphate group from glycogen phorphorylase by the enzyme ____________.

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protein ph...

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What are the two regulatory controls for phosphorylase kinase?

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Phosphorylase kinase is activa...

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The ____________ enzyme catalyzes the phosphorylation of glycogen phosphorylase.


A) reducing
B) ɑ-1,6-glycosidic
C) phosphorylase kinase
D) ɑ-1,4-glycoside
E) nonreducing
F) phosphorylase a
G) glucose 6-phosphatase
H) UTP-glucose
I) calmodulin
J) phosphorolysis
K) epinephrine
L) glucagon

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The process by which a bond is cleaved by the addition of orthophosphate is ____________.


A) reducing
B) ɑ-1,6-glycosidic
C) phosphorylase kinase
D) ɑ-1,4-glycoside
E) nonreducing
F) phosphorylase a
G) glucose 6-phosphatase
H) UTP-glucose
I) calmodulin
J) phosphorolysis
K) epinephrine
L) glucagon

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____________ is the liver enzyme that cleaves the phosphate from glucose 6-phosphate.


A) reducing
B) ɑ-1,6-glycosidic
C) phosphorylase kinase
D) ɑ-1,4-glycoside
E) nonreducing
F) phosphorylase a
G) glucose 6-phosphatase
H) UTP-glucose
I) calmodulin
J) phosphorolysis
K) epinephrine
L) glucagon

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Why is the T state of glycogen phosphorylase less active?


A) The adjacent amino acids are not phosphorylated; thus the catalysis cannot be carried out.
B) The active site is partially blocked.
C) ATP cannot be bound by the T state.
D) All of the above.
E) None of the above.

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What is the function of liver glycogen degradation?


A) to export glucose to other tissues when glucose levels are low
B) to maintain glucose levels after a large meal
C) to provide for the large energy needs of the liver
D) All of the above.
E) None of the above.

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____________ takes place instead of hydrolysis in glycogen breakdown.


A) reducing
B) ɑ-1,6-glycosidic
C) phosphorylase kinase
D) ɑ-1,4-glycoside
E) nonreducing
F) phosphorylase a
G) glucose 6-phosphatase
H) UTP-glucose
I) calmodulin
J) phosphorolysis
K) epinephrine
L) glucagon

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Draw a structure showing the most common linkage between glucose units found in glycogen.

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The structure should...

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Why can't the glucose 1-phosphate diffuse out of the cell?

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There is no membrane transport...

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The hormone ____________ signifies the starved state.


A) reducing
B) ɑ-1,6-glycosidic
C) phosphorylase kinase
D) ɑ-1,4-glycoside
E) nonreducing
F) phosphorylase a
G) glucose 6-phosphatase
H) UTP-glucose
I) calmodulin
J) phosphorolysis
K) epinephrine
L) glucagon

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What path, in addition to the cAMP-induced signal transduction, is used in the liver to stimulate glycogen breakdown by epinephrine?

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In the liver, epinephrine also binds to ...

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Which liver enzyme is deficient in Hers disease?


A) phosphorylase
B) transferase
C) glucosidase
D) phosphoglucomutase
E) None of the above.

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The type of bond that is located at the branch points in glycogen is ____________.


A) reducing
B) ɑ-1,6-glycosidic
C) phosphorylase kinase
D) ɑ-1,4-glycoside
E) nonreducing
F) phosphorylase a
G) glucose 6-phosphatase
H) UTP-glucose
I) calmodulin
J) phosphorolysis
K) epinephrine
L) glucagon

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What physiological conditions render phosphorylase b less active?


A) high ATP, high AMP, and glucose 6-phosphate levels
B) high ATP and low calcium ion levels
C) high ATP and high glucose 6-phosphate levels
D) All of the above.
E) None of the above.

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The hydrolysis catalyzed by α-1,6-glucosidase releases a(n) ______________ molecule.

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The major site(s) of glycogen storage is (are) :


A) adipose tissue.
B) liver.
C) skeletal muscle.
D) B and C.
E) A, B, and C.

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