Question 1

The first intermediate formed from glucose in the pentose phosphate pathway is

Accepted Answer

A)   6-phosphogluconolactone.
B)   6-phosphogluconate.
C)   fructose 6-phosphate.
D)   ribulose 5-phosphate.
E)   glucose 1-phosphate.

Question 2

The principal regulatory factor governing the rate of the pentose phosphate pathway is the level of

Accepted Answer

A)   ATP
B)   ADP
C)   AMP
D)   NAD+
E)   NADP+

Question 3

In the reaction below, catalyzed by transketolase, what is compound Z? Z + ribose-5-P  glyceraldehyde-3-P + sedoheptulose-7-P

Accepted Answer

A)   erythrose 4-phosphate
B)   fructose 6-phsophate
C)   6-phosphogluconate
D)   ribulose
E)   xylulose 5-phosphate

Question 4

All of the following molecules are formed in the pentose phosphate pathway EXCEPT

Accepted Answer

A)   carbon dioxide
B)   pentose 5-phosphate
C)   NADPH
D)   NADH
E)   glyceraldehyde 3-phosphate

Question 5

In liver, the hexose monophosphate shunt is the principal source of

Accepted Answer

A)   carbon dioxide.
B)   glucose 6-phosphate.
C)   the reduction of NAD.
D)   fructose 6-phosphate.
E)   ribose 5-phosphate.

Question 6

What is the major difference in the synthesis of N- and O-linked carbohydrate residues on glycoproteins?

Accepted Answer

A)   N-linked has branches
B)   N-linked has mannose
C)   O-linked is assembled on a dolichol intermediate
D)   O-linked is assembled on the protein
E)   Synthesis of O-linked requires energy

Question 7

Hyaluronic acid consists of repeating units of

Accepted Answer

A)   glucose and fructose.
B)   glucuronic acid and N-acetylglucosamine.
C)   galactose and N-acetylgalactosamine.
D)   glucuronic acid and N-acetylgalactosamine.
E)   glucuronic acid and N-acetylgalactosamine-4-sulfate.

Question 8

Which statement is FALSE?

Accepted Answer

A)   Hyaluronic acid is a glycosaminoglycan (GAG)  but not a proteoglycan.
B)   In proteoglycans, the GAGs are linked to serine residues in the core protein.
C)   The major sugar components of proteoglycans are pentoses, such as xylose, and N-acetylamino sugars.
D)   proteoglycans typically carry many negative charges.
E)   Hurler's disease results from deficient activity of an enzyme normally involved in the degradation of GAGs.

Question 9

Which of the following generates NADPH?

Accepted Answer

A)   Glycolysis
B)   hexose monophosphate shunt
C)   Krebs cycle
D)   Gluconeogenesis
E)   Glycogenolysis

Question 10

Proteoglycan monomers contain

Accepted Answer

A)   glycosaminoglycans.
B)   derivatives of mannosamine.
C)   either mannuronic acid or iduronic acid.
D)   repeating trisaccharide units.

Question 11

HMP shunt occurs in

Accepted Answer

A)   nucleus.
B)   nucleus and microsomes.
C)   cytosol.
D)   mitochondria.

Question 12

A nine carbon acid found in a terminal position in the oligosaccharide portion of many glycoproteins is

Accepted Answer

A)   hyaluronic acid.
B)   sialic acid.
C)   iduronic acid.
D)   glucuronic acid.
E)   gluconic acid.

Question 13

All of the following are glycosaminoglycans EXCEPT

Accepted Answer

A)   hyaluronate.
B)   heparin.
C)   chondroitin sulfate.
D)   keratan sulfate.
E)   glucuronate.

Question 14

Carbon number 1 of glucose in the hexose monophosphate shunt is converted to

Accepted Answer

A)   ribose.
B)   deoxyribose.
C)   carbon dioxide.
D)   fatty acid.

Question 15

Which of the following heteropolysaccharides is frequently used clinically as an anticoagulant?

Accepted Answer

A)   hyaluronic acid
B)   keratin sulfate
C)   heparin
D)   dermatin sulfate
E)   chondroitin sulfate

Exam 16: Carbohydrate Metabolism II: Special Pathways and Glycoconjugates

Which statement is FALSE?

Correct Answer
verified

HMP shunt occurs in

Correct Answer
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Carbon number 1 of glucose in the hexose monophosphate shunt is converted to

Correct Answer
verified

The principal regulatory factor governing the rate of the pentose phosphate pathway is the level of

Correct Answer
verified

Which of the following generates NADPH?

Correct Answer
verified

What is the major difference in the synthesis of N- and O-linked carbohydrate residues on glycoproteins?

Correct Answer
verified

The first intermediate formed from glucose in the pentose phosphate pathway is

Correct Answer
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All of the following molecules are formed in the pentose phosphate pathway EXCEPT

Correct Answer
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Which of the following heteropolysaccharides is frequently used clinically as an anticoagulant?

Correct Answer
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In the reaction below, catalyzed by transketolase, what is compound Z? Z + ribose-5-P <--> glyceraldehyde-3-P + sedoheptulose-7-P

Correct Answer
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Proteoglycan monomers contain

Correct Answer
verified

In liver, the hexose monophosphate shunt is the principal source of

Correct Answer
verified

All of the following are glycosaminoglycans EXCEPT

Correct Answer
verified

A nine carbon acid found in a terminal position in the oligosaccharide portion of many glycoproteins is

Correct Answer
verified

Hyaluronic acid consists of repeating units of

Correct Answer
verified

Exam 16: Carbohydrate Metabolism II: Special Pathways and Glycoconjugates

Which statement is FALSE?

Correct AnswerverifiedShow Answer

HMP shunt occurs in

Correct AnswerverifiedShow Answer

Carbon number 1 of glucose in the hexose monophosphate shunt is converted to

Correct AnswerverifiedShow Answer

The principal regulatory factor governing the rate of the pentose phosphate pathway is the level of

Correct AnswerverifiedShow Answer

Which of the following generates NADPH?

Correct AnswerverifiedShow Answer

What is the major difference in the synthesis of N- and O-linked carbohydrate residues on glycoproteins?

Correct AnswerverifiedShow Answer

The first intermediate formed from glucose in the pentose phosphate pathway is

Correct AnswerverifiedShow Answer

All of the following molecules are formed in the pentose phosphate pathway EXCEPT

Correct AnswerverifiedShow Answer

Which of the following heteropolysaccharides is frequently used clinically as an anticoagulant?

Correct AnswerverifiedShow Answer

In the reaction below, catalyzed by transketolase, what is compound Z? Z + ribose-5-P <--> glyceraldehyde-3-P + sedoheptulose-7-P

Correct AnswerverifiedShow Answer

Proteoglycan monomers contain

Correct AnswerverifiedShow Answer

In liver, the hexose monophosphate shunt is the principal source of

Correct AnswerverifiedShow Answer

All of the following are glycosaminoglycans EXCEPT

Correct AnswerverifiedShow Answer

A nine carbon acid found in a terminal position in the oligosaccharide portion of many glycoproteins is

Correct AnswerverifiedShow Answer

Hyaluronic acid consists of repeating units of

Correct AnswerverifiedShow Answer

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