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Formalin is useful in the histology laboratory because it


A) introduces microorganisms that help to decompose the brain after death.
B) halts the enzyme process that breaks down brain tissue after death.
C) quickly removes the blood from the brain.
D) softens the brain tissue.
E) produces a reversible lesion of the brain.

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Immunocytochemical techniques take advantage of the specific affinity of antibodies for


A) dopamine receptors.
B) glial cell nuclei.
C) cytogens.
D) a peptide or protein molecule.
E) white blood cells.

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The ________ labeling method uses chemicals that are taken up by dendrites and then transported through axons toward terminal buttons.


A) retrograde
B) axoplasmic
C) anterograde
D) heterosynaptic
E) homosynaptic

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Killing neurons by overstimulating them is caused by


A) electric current via wire.
B) anesthesia.
C) excitatory amino acids.
D) sucking away brain tissue.
E) radio-frequency current.

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Successive pages of a stereotaxic atlas refer to


A) various distances relative to the bottom of the brain.
B) the distance from the top of the skull.
C) various distances relative to bregma.
D) various distances relative to the midline.
E) horizontal sections of the brain.

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A scientist wishing to locate small bundles of axons in the human brain would be advised to use the _______ technique.


A) transneuronal tracing
B) PET scan
C) fMRI
D) diffuser tension imaging
E) computerized tomography

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The ________ technique would be used to trace efferent axons from a brain region.


A) retrograde labeling method
B) staining produced by methylene blue
C) scanning electron microscopy
D) anterograde labeling method
E) computerized tomography

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Which of the following is true of confocal laser scanning microscopy?


A) This technique is limited to a magnification of X100.
B) The confocal laser scanning microscope uses an electron beam to scan a thin slice of tissue.
C) The procedure can be used to visualize living brain cells.
D) This technique can only be used for tissue subjected to formalin.
E) This technique has less resolution than does light microscopy.

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One of the oldest methods used in neuroscience to study brain function is


A) immunocytochemistry.
B) stereotaxic surgery.
C) autoradiography.
D) experimental ablation.
E) twin-study methods.

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The ________ method uses an antibody linked to a radioactive molecule to bind to a peptide or an enzyme in brain tissue.

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The ________ technique can be used to visualize differences between white matter and gray matter in a living subject.


A) confocal laser scanning microscopy
B) transneuronal tracing procedure
C) magnetic resonance imaging
D) stereotaxic procedure
E) computerized tomography

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The brain imaging method with the best spatial resolution is


A) CT.
B) PET.
C) MRI.
D) fMRI.
E) electroencephalograph.

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If one twin has Syndrome Z and the other is more likely to have it than the average non-related individual, then Syndrome Z is


A) concordant.
B) discordant.
C) dissimilar.
D) similar.
E) dizygotic.

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The ________ technique uses a radio frequency wave to excite hydrogen atoms in the brain to create an image of the living human brain.


A) computerized tomography
B) microdialysis
C) magnetic resonance imaging
D) retrograde tracing
E) PET scan

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Which of the following is true of the anterograde labeling procedure?


A) A target molecule is injected into the gut.
B) The target molecule is transported from the axon terminals back to the soma and dendrites.
C) The target molecule is taken up by the dendrites of cells in the injection zone and transported through axons.
D) Eventually the target molecule fills cell bodies.
E) A light microscopy method is used to visualize the cells in a section that contains the target molecules.

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Stereotaxic apparatuses exist for


A) mice.
B) rats.
C) humans.
D) rats and mice only.
E) mice, rats, and humans (among others) .

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What is the rationale for experimental ablation method?

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The notion is that changes in ...

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Explain the rationale behind the optogenetic methods.

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The method can be used to stimulate or i...

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________ can be translated as "writing with one's own radiation."

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Which of the following represents a problem for interpreting the effects of a brain lesion on behavior?


A) Brain lesions are difficult to produce in animals.
B) The lesion may impair the function of a distant neural structure, which in turn alters behavior.
C) Behaviors are difficult to monitor reliably in animals.
D) Each brain structure is isolated from the others.
E) Since only 10 percent of the brain is in use, there is only a 10 percent chance that damaging a structure will induce a behavioral change.

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