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If HIV is mutated such that its tat protein is less able to bind to mRNA, the most likely result will be


A) more initiation of transcription.
B) less initiation of transcription.
C) the termination of more partial transcripts, and thus the making of fewer complete transcripts.
D) the termination of fewer partial transcripts, and thus the making of more complete transcripts.
E) a reduction in the stability of complete transcripts.

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A small RNA product that would be useful for defense against invading viruses is a(n) _______, since it results in the degradation of mRNA transcripts.

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In its role in protein regulation, ubiquitin is most closely associated with


A) alternative splicing.
B) proteasomes.
C) siRNAs.
D) miRNAs.
E) Xist.

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Refer to the figure showing an experiment on female honey bees. Refer to the figure showing an experiment on female honey bees.   Which conclusion can be drawn from this experiment? A)  Decreasing DNA methylation causes larvae destined to become worker bees to instead become queens. B)  Increasing DNA methylation causes larvae destined to become worker bees to instead become queens. C)  Decreasing DNA methylation causes larvae destined to become queens to instead become worker bees. D)  Increasing DNA methylation causes larvae destined to become queens to instead become worker bees. E)  More data are needed before conclusions can be drawn. Which conclusion can be drawn from this experiment?


A) Decreasing DNA methylation causes larvae destined to become worker bees to instead become queens.
B) Increasing DNA methylation causes larvae destined to become worker bees to instead become queens.
C) Decreasing DNA methylation causes larvae destined to become queens to instead become worker bees.
D) Increasing DNA methylation causes larvae destined to become queens to instead become worker bees.
E) More data are needed before conclusions can be drawn.

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Specific transcription factors would be able to recognize sequences in _______ gene promoter regions.

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Sigma factors bind to


A) proteins.
B) DNA.
C) RNA.
D) lipids.
E) carbohydrates.

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A certain operon has structural genes that encode enzymes involved in the synthesis of a glycopeptide.This system is likely to be _______, and _______ will most likely bind to the operator.


A) inducible; the glycopeptide
B) inducible; one or more molecules used in the production of the glycopeptide
C) repressible; the glycopeptide
D) repressible; one or more molecules used in the production of the glycopeptide
E) repressible; no molecules

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With a small number of genes, a cell can use _______ to achieve a large variety of protein products.

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alternativ...

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If you wanted to build a complex organism with differentiated cells, which type of molecule would not help achieve that goal?


A) General transcription factors
B) Varied RNA polymerases
C) Nuclear envelopes
D) Operons
E) Specific transcription factors

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Proteins that are produced all the time at a constant rate are _______ proteins.


A) inducible
B) repressible
C) regulatory
D) constitutive
E) metabolic

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Which statement about histone modifications is false?


A) They cause some genes to be transcriptionally activated.
B) They can result in the repression of gene transcription.
C) They can be inherited from parental cells in a Mendelian fashion.
D) They are the initial step in Barr body formation.
E) They are due to acetylation, phosphorylation, or methylation.

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Methylation most often occurs to _______ that are next to _______.


A) adenines; cytosines
B) adenines; guanines
C) cytosines; adenines
D) cytosines; guanines
E) guanines; adenines

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A mutagenesis screen uncovers two discrete mutations, each for a single gene of a given operon that contains the genes that control a biosynthetic pathway.Which phenomenon would likely be observed in an organism that carries both of these mutations?


A) Partial linkage
B) Complete linkage
C) Epistasis
D) Recessive lethality
E) Complete dominance/recessiveness

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Gene regulation by tat in HIV occurs at the level of


A) transcription initiation.
B) transcription elongation.
C) mRNA stability.
D) translation initiation.
E) translation elongation.

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In a bacteriophage undergoing a lytic phase, the early gene products _______ the host genes and _______ the late genes.


A) stimulate; stimulate
B) stimulate; have no effect on
C) stimulate; inhibit
D) inhibit; stimulate
E) inhibit; inhibit

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DNA methyltransferase


A) adds methyl groups to DNA.
B) adds methyl groups to DNA but only during DNA replication.
C) adds methyl groups to DNA but only during reverse transcription.
D) removes methyl groups from DNA.
E) keeps track of where methyl groups have been added.

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HIV, which causes AIDS, is a(n)


A) bacteriophage.
B) double-stranded DNA virus.
C) single-stranded DNA virus.
D) a type of herpes virus.
E) retrovirus.

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The Barr body indicates


A) X chromosome inactivation.
B) cell death.
C) genomic imprinting.
D) posttranslational control of eukaryotic gene expression.
E) stress response.

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The number of Barr bodies in a mammalian cell will be


A) equal to the number of X chromosomes in the same cell.
B) one more than the number of X chromosomes in the same cell.
C) one fewer than the number of X chromosomes in the same cell.
D) one more than the number of X chromosomes in the same cell in a male, but one fewer than the number of X chromosomes in the same cell in a female.
E) one fewer than the number of X chromosomes in the same cell in a male, but one more than the number of X chromosomes in the same cell in a female.

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The TATA box in eukaryotes is most similar to _______ in prokaryotes.


A) sigma factors
B) the entire promoter
C) a consensus sequence in the promoter
D) an operator
E) an inducer

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