Question 1

What percentage of band neutrophils is present in the peripheral blood?

Accepted Answer

A)   1-4%
B)   2-6%
C)   10-12%
D)   4-8%
E)   None of the above

Question 2

The stage in granulocyte maturation where the nucleus appears kidney shaped is evident in what cell?

Accepted Answer

A)   Promyelocyte
B)   Band neutrophil
C)   Metamyelocyte
D)   Myelocyte
E)   None of the above

Question 3

The hematopoietic system consists of the:

Accepted Answer

A)   Thymus
B)   Bone marrow
C)   Liver
D)   Spleen
E)   All of the above

Question 4

By increasing hematopoiesis, the hematopoietic system can respond to stimuli such as:

Accepted Answer

A)   Infection
B)   Bleeding
C)   Hypoxia
D)   All of the above
E)   None of the above

Question 5

Ultimately, megakaryocytes lead to the formation of non-nucleated, cytoplasmic fragments called:

Accepted Answer

A)   Granulocytes
B)   Thrombocytes
C)   Lymphocytes
D)   Monocytes
E)   None of the above B

Question 6

What is the sequence of maturity for the erythrocyte?

Accepted Answer

A)   Rubriblast, prorubricyte, metarubricyte, rubricyte, reticulocyte, erythrocyte
B)   Prorubricyte, rubriblast, metarubricyte, reticulocyte, erythrocyte, rubricyte
C)   Metarubricyte, rubriblast, reticulocyte, erythrocyte, prorubricyte, rubricyte
D)   Rubricyte, metarubricyte, rubriblast, erythrocyte, reticulocyte, prorubricyte
E)   Rubriblast, prorubricyte, rubricyte, metarubricyte, reticulocyte, erythrocyte

Question 7

What percentage of lymphocytes is present in peripheral blood?

Accepted Answer

A)   50-70%
B)   20-44%
C)   10-30%
D)   5-10%
E)   None of the above

Question 8

Reactive lymphocytes are present in the evaluation of certain diseases such as:

Accepted Answer

A)   Infectious mononucleosis
B)   Cancer
C)   Bacterial infections
D)   Tumors
E)   Anemias A

Question 9

An alteration in the megakaryoblast might occur in which disease state?

Accepted Answer

A)   Iron-deficiency anemia
B)   Chronic granulocytic leukemia
C)   Chronic lymphocytic leukemia
D)   Thalassemia
E)   None of the above

Question 10

What stages do both basophils and eosinophils pass through in their sequence of maturity?

Accepted Answer

A)   Promyelocyte, myelocyte, band cell, segmented cell
B)   Myeloblast, promyelocyte, myelocyte, band cell, segmented cell
C)   Myelocyte, metamyelocyte, band cell, segmented cell
D)   Band cell, myelocyte, metamyelocyte, segmented cell
E)   None of the above

Question 11

What percentage of erythrocytes is functional in peripheral blood after release from the bone marrow?

Accepted Answer

A)   70%
B)   50%
C)   80%
D)   100%
E)   None of the above

Question 12

What function do mast cells and basophils serve?

Accepted Answer

A)   Oxygen supply to tissues
B)   Phagocytosis in parasitic infections
C)   Histamine release in allergic reactions
D)   Cell-mediated immunity
E)   None of the above

Question 13

The first sign of neutrophilic differentiation and appearance of secondary granules is evident in what cell type?

Accepted Answer

A)   Promyelocyte
B)   Myelocyte
C)   Segmented neutrophil
D)   Metamyelocyte
E)   None of the above

Question 14

What characteristics are helpful in the identification of monocytes?

Accepted Answer

A)   Gray-blue cytoplasm
B)   Digestive vacuoles
C)   Lacy, delicate chromatin and indented nucleus
D)   "Ground-glass" appearance of cytoplasm with evenly distributed fine granules
E)   All of the above

Question 15

Evaluate the clinical use of interleukins:

Accepted Answer

A)   Wound healing
B)   Activating lymphocytes
C)   Assisting in growth of bone marrow
D)   B and C
E)   All are correct E

Question 16

Plasmacytes represent the end stage of what cell lineage?

Accepted Answer

A)   B lymphocytes
B)   T lymphocytes
C)   Prolymphocytes
D)   Lymphoblasts
E)   Megakaryocyte

Question 17

What is the average diameter of a normal erythrocyte?

Accepted Answer

A)   3-5 µm
B)   2-4 µm
C)   8-10 µm
D)   7-8 µm
E)   None of the above

Question 18

What disease state can be associated with the presence of tissue neutrophils in bone marrow?

Accepted Answer

A)   Myelocytic leukemia
B)   Erythroleukemia
C)   Acute lymphocytic leukemia
D)   Non-Hodgkin's lymphoma
E)   None of the above

Question 19

What color does the cytoplasm of eosinophils retain on Wright's stain?

Accepted Answer

A)   Bluish-purple
B)   Reddish-orange
C)   Reddish-pink
D)   Purple-black
E)   None of the above

Question 20

What is meant by medullary hematopoiesis?

Accepted Answer

A)   Hematopoiesis in the spleen
B)   Hematopoiesis in marrow
C)   Hematopoiesis in liver
D)   Hematopoiesis in thymus
E)   None of the above

Exam 1: Morphology of Human Blood and Marrow Cells: Hematopoiesis

What percentage of band neutrophils is present in the peripheral blood?

Correct AnswerverifiedShow Answer

The stage in granulocyte maturation where the nucleus appears kidney shaped is evident in what cell?

Correct AnswerverifiedShow Answer

The hematopoietic system consists of the:

Correct AnswerverifiedShow Answer

By increasing hematopoiesis, the hematopoietic system can respond to stimuli such as:

Correct AnswerverifiedShow Answer

Ultimately, megakaryocytes lead to the formation of non-nucleated, cytoplasmic fragments called:

Correct AnswerverifiedB

What is the sequence of maturity for the erythrocyte?

Correct AnswerverifiedShow Answer

What percentage of lymphocytes is present in peripheral blood?

Correct AnswerverifiedShow Answer

Reactive lymphocytes are present in the evaluation of certain diseases such as:

Correct AnswerverifiedA

An alteration in the megakaryoblast might occur in which disease state?

Correct AnswerverifiedShow Answer

What stages do both basophils and eosinophils pass through in their sequence of maturity?

Correct AnswerverifiedShow Answer

What percentage of erythrocytes is functional in peripheral blood after release from the bone marrow?

Correct AnswerverifiedShow Answer

What function do mast cells and basophils serve?

Correct AnswerverifiedShow Answer

The first sign of neutrophilic differentiation and appearance of secondary granules is evident in what cell type?

Correct AnswerverifiedShow Answer

What characteristics are helpful in the identification of monocytes?

Correct AnswerverifiedShow Answer

Evaluate the clinical use of interleukins:

Correct AnswerverifiedE

Plasmacytes represent the end stage of what cell lineage?

Correct AnswerverifiedShow Answer

What is the average diameter of a normal erythrocyte?

Correct AnswerverifiedShow Answer

What disease state can be associated with the presence of tissue neutrophils in bone marrow?

Correct AnswerverifiedShow Answer

What color does the cytoplasm of eosinophils retain on Wright's stain?

Correct AnswerverifiedShow Answer

What is meant by medullary hematopoiesis?

Correct AnswerverifiedShow Answer

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B

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A

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E

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