Question 1

From the following polynucleotide sequence, one would conclude which of the following? ACCAGTCG

Accepted Answer

A)  the base found at the 3' end of the molecule is adenine
B)  the base found at the 5' end of the molecule is adenine
C)  the terminal adenosine contains a free 3' hydroxyl group
D)  the terminal guanosine contains a free 5' phosphate group
E)  none of the above

Question 2

Show the typical hydrogen bonds that from when adenine pairs with its complimentary base.

Accepted Answer

The answer of Show the typical hydrogen bonds that from...

Question 3

Draw the two forms of a phosphodiester bond that can occur under physiological pH. If the pKa for this conversion is 6.2, what form predominates in the lysosome where the pH is about 5?

Accepted Answer

<img  loading="lazy" src="/assets/images/blured-textbook.svg" class="d-inline m-1" alt="blured image" width="139" height="30"> The protonated form...

Question 4

Which of the following correctly describes the structure of a nucleotide?

Accepted Answer

A)  adenine is bound via a link between N-7 and C-1 of ribose
B)  phosphates are always bound to C-2 of ribose
C)  cytosine is bound via a link between the amine on C-4 and C-1 of ribose
D)  guanine is bound via a link between N-9 and C-1 of ribose
E)  none of the above

Question 5

Which of the following base pairs would have 2 hydrogen bonds and a distance between C-1' of 1.08 nm?

Accepted Answer

A)  A-C
B)  G-C
C)  A-T
D)  G-T
E)  none of the above

Question 6

Which of the following represents a palindromic sequence?

Accepted Answer

A)  ACCTTCCA
B)  ATTCCAAT
C)  GATTAATC
D)  GGTAATCC
E)  none of the above

Question 7

Which of the following secondary structures is correctly identified?

Accepted Answer

A)  Z-DNA: left-handed DNA with pyrimidines in the syn conformation and purines in the anti conformation
B)  hairpin structure: self-complimentary single stranded molecules that form a parallel helix
C)  cruciform: a double hairpin formed in a region of palindromic DNA
D)  H-DNA: triple helical structure that results when Watson-Crick base pairing does not form and instead, Hoogsteen base pairing occurs
E)  none of the above

Question 8

Which of the following is the most commonly observed nucleic acid form for storing of genomic information?

Accepted Answer

A)  single-stranded DNA
B)  double-stranded DNA
C)  single-stranded RNA
D)  double-stranded RNA
E)  hybrid molecules of DNA and RNA

Exam 4: Nucleic Acids

Which of the following is the most commonly observed nucleic acid form for storing of genomic information?

Correct Answer
verified

Which of the following secondary structures is correctly identified?

Correct Answer
verified

Show the typical hydrogen bonds that from when adenine pairs with its complimentary base.

Correct Answer
verified

Which of the following correctly describes the structure of a nucleotide?

Correct Answer
verified

From the following polynucleotide sequence, one would conclude which of the following? ACCAGTCG

Correct Answer
verified

Draw the two forms of a phosphodiester bond that can occur under physiological pH. If the pK_a for this conversion is 6.2, what form predominates in the lysosome where the pH is about 5?

Correct Answer
verified
The protonated form...
View Answer

Which of the following represents a palindromic sequence?

Correct Answer
verified

Which of the following base pairs would have 2 hydrogen bonds and a distance between C-1' of 1.08 nm?

Correct Answer
verified

Exam 4: Nucleic Acids

Which of the following is the most commonly observed nucleic acid form for storing of genomic information?

Correct AnswerverifiedShow Answer

Which of the following secondary structures is correctly identified?

Correct AnswerverifiedShow Answer

Show the typical hydrogen bonds that from when adenine pairs with its complimentary base.

Correct AnswerverifiedShow Answer

Which of the following correctly describes the structure of a nucleotide?

Correct AnswerverifiedShow Answer

From the following polynucleotide sequence, one would conclude which of the following? ACCAGTCG

Correct AnswerverifiedShow Answer

Draw the two forms of a phosphodiester bond that can occur under physiological pH. If the pKa for this conversion is 6.2, what form predominates in the lysosome where the pH is about 5?

Correct Answerverified The protonated form...View AnswerShow Answer

Which of the following represents a palindromic sequence?

Correct AnswerverifiedShow Answer

Which of the following base pairs would have 2 hydrogen bonds and a distance between C-1' of 1.08 nm?

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Draw the two forms of a phosphodiester bond that can occur under physiological pH. If the pK_a for this conversion is 6.2, what form predominates in the lysosome where the pH is about 5?

Correct Answer
verified
The protonated form...
View Answer

Correct Answer
verified

Correct Answer
verified