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How are barbiturates usually classified?


A) duration of action
B) price
C) chemical structure
D) strength of hypnotic effect

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Withdrawal from long-term use of sedative-hypnotic drugs is characterized by


A) aching,high blood pressure,drowsiness.
B) anxiety,insomnia,nausea,seizures.
C) rapid mood swings.
D) minor discomfort,but no serious symptoms.

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B

What has kept paraldehyde from being widely used?


A) danger to the CNS
B) bad taste and odor
C) danger to the respiratory system
D) irritation to the gastric system

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The majority of "huffers" (users of inhalants)are above age 25.

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Which of the following drugs could theoretically be used to treat barbiturate withdrawal?


A) methamphetamine
B) fluoxetine
C) alcohol
D) modafinil

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What household product contains nitrous oxide?


A) fuel gas
B) hair spray
C) spray paint
D) whipped cream dispensers

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When benzodiazepines bind to their receptor site,they


A) release barbiturates.
B) block acetylcholine receptors.
C) reduce the membrane electrical potential.
D) enhance the inhibitory effects of GABA.

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Sedative-hypnotic agents bind to which receptors in the brain?


A) glutamate
B) GHB
C) serotonin
D) GABA

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The modern era of abuse of volatile solvents by young people can be traced to a 1959 newspaper report of


A) gasoline huffing.
B) glue sniffing.
C) lead paint poisoning.
D) nitrite abuse.

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Animal self-administration experiments and studies of drug choice among humans indicate that


A) benzodiazepines have no dependence liability.
B) rats and people are very different in the drugs they choose to self-administer.
C) short-acting barbiturates are more likely to lead to dependence than any of the benzodiazepines.
D) all of the benzodiazepines have high dependence liability.

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Inhalant use has traditionally been more common among


A) poor Hispanic and Native American youth.
B) middle-class white children.
C) middle-class black children.
D) construction workers.

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A

Discuss the use of medications as hypnotics (sleeping pills).What types of drugs are used,and what are some of the concerns associated with the use of sleeping pills? Are there any alternatives to drug use?

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Although many people complain of poor sl...

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Anecdotally,__________ (or "poppers") are used to enhance sexual pleasure.


A) nitrous oxide
B) amyl nitrite
C) GHB
D) Rohypnol

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Nitrous oxide ("laughing gas")is a Schedule I controlled substance.

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Among the barbiturates,when prescribing a sleeping pill (hypnotic) ,physicians would usually choose a


A) higher dose of a short-acting drug.
B) lower dose of a long-acting drug.
C) higher dose of a long-acting drug.
D) lower dose of a short-acting drug.

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The usual recreational dose of GHB when taken alone is about


A) 10-20 milligrams.
B) 100 micrograms.
C) 1-5 grams.
D) 100-200 grams.

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  -GHB has been used for several purposes.Describe its recent history of various medical and recreational uses and its status as a controlled substance. -GHB has been used for several purposes.Describe its recent history of various medical and recreational uses and its status as a controlled substance.

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GHB was sold as a dietary supplement and used to stimulate muscle growth.In high doses,GHB has alcohol-like effects,and its recreational use led to banning it from dietary supplements in 1990.Its use as a date-rape drug led Congress to direct that GHB be placed on Schedule I in 2000.In 2002,a prescription version (Xyrem)was made available for treating narcolepsy.Xyrem is on Schedule III.

Explain how a drug's rate of onset and duration of action affect psychological dependence and withdrawal.Give examples from this chapter.

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Drugs with rapid onset of action will be...

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Librium (chlordiazepoxide) and Valium (diazepam) were the first widely sold


A) benzodiazepines.
B) barbiturates.
C) methaqualones.
D) sedatives.

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Benzodiazepines replaced barbiturates primarily because they were believed to be safer.

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