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In most of the cells in the body there is an electrical difference such that the inside of cells is positive with respect to the outside.

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The properties of the plasma membranes of epithelial cells lining hollow organs or tubes are similar,regardless of the orientation of the cells.

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Specific proteins in the membranes mediate movement of lipid-soluble molecules into cells.

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The reason solutions for injection or infusion into people normally contain either 150 mM NaCl or 300 mM glucose is that these


A) Solutes are necessary for metabolism
B) Solutions are hypertonic to the blood and cells
C) Solutions are hypoosmotic to the blood and cells
D) Solutions are isotonic to the blood and cells
E) Solutions contain penetrating solutes

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Which of the following statements regarding the active transport of solutes across cell membranes is correct?


A) Primary active transporters are ATPases and secondary active transporters are not
B) Secondary active transporters require binding of Na ion on the extracellular side of the membrane to transport other solutes either into or out of the cell
C) Solutes transported across cell membranes by primary active transport include glucose, Na ion and Ca ion
D) Both primary active transporters are ATPases and secondary active transporters are not and secondary active transporters require binding of Na ion on the extracellular side of the membrane to transport other solutes either into or out of the cell are correct
E) All of the choices are correct

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When a solute,X,is placed in compartment A of a two compartment container and allowed to diffuse to compartment B and attain diffusion equilibrium,then


A) There will no longer be any movement of solutes between compartments
B) Solutes will be moving in both directions equally
C) Solutes will only continue to move from A to B
D) Solutes will only continue to move from B to A
E) Solutes will continue to move to the side with the higher concentration

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Which of the following is a feature that distinguishes active transport from facilitated diffusion?


A) Saturability
B) Requirement for a carrier molecule
C) Specificity
D) Presence of a transport maximum
E) Requirement for metabolic energy

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Pinocytosis is a method by which molecules can leave cells whose membranes are impermeable to the molecules.

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If a cell is placed in a hyperosmotic solution,it


A) Will swell
B) Will shrink
C) Will stay the same size
D) May swell, shrink or stay the same size, depending upon the concentration of penetrating and nonpenetrating solutes in the solution

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Because of the active transport of Na+ and K+,the intracellular concentration of Na+ is lower than the extracellular concentration,whereas the reverse is true for K+.

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During the active transport of glucose across an epithelium,energy is used to


A) Power the Na, K-ATPase pump
B) Power the Na-glucose cotransporter
C) Synthesize insulin, which is necessary for glucose reabsorption
D) Maintain the transport maximum for glucose
E) Power the facilitated diffusion of glucose across the basolateral membrane of the epithelial cell

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If the ATP-generating mechanisms in a cell are poisoned and the cell has depleted its ATP reserves,


A) Primary active transport of molecules would cease immediately
B) Secondary active transport of molecules would cease immediately
C) Eventually there will be no potential difference across the membrane
D) Both primary active transport of molecules would cease immediately and secondary active transport of molecules would cease immediately are correct
E) Both primary active transport of molecules would cease immediately and eventually there will be no potential difference across the membrane are correct

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In the body,K ions behave as if they are penetrating solutes because they are actively transported into cells.

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Net movement of solute across an epithelium that is permeable to water is always accompanied by movement of water in the opposite direction.

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Which of the following solutions is not isotonic to human cells?


A) 300 mM glucose
B) 300 mM urea
C) 100 mM MgCl2
D) 300 mOsm NaCl

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Adding one mole of NaCl to one liter of water will lower the water concentration twice as much as adding one mole of glucose.

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At any given concentration difference,the rate of diffusion across a permeable surface will be greater for small molecules than for larger ones.

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The mediated transport of a substance across a plasma membrane


A) Depends upon the binding of that substance to a specific site on the membrane protein
B) Depends upon movement of proteins from one side of the membrane to the other
C) Always increases in direct proportion to the increasing concentration of the substance on one side of the membrane
D) Both depends upon the binding of that substance to a specific site on the membrane protein and depends upon movement of proteins from one side of the membrane to the other are correct
E) All of the choices are correct

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Which of the following statements regarding the active transport of molecules across cell membranes is correct?


A) Both primary and secondary active transport are dependent upon energy derived from ATP
B) In secondary active-transport systems in which Na ions are bound to carriers, the actively transported solute always follows Na ions across the membrane
C) In secondary active-transport systems in which Na ions are bound to carriers, the actively transported solute always moves across the membrane in the direction opposite of Na ion movement
D) Both primary and secondary active transport are dependent upon energy derived from ATP and in secondary active-transport systems in which Na ions are bound to carriers, the actively transported solute always follows Na ions across the membrane are correct
E) Both primary and secondary active transport are dependent upon energy derived from ATP and in secondary active-transport systems in which Na ions are bound to carriers, the actively transported solute always moves across the membrane in the direction opposite of Na ion movement are correct

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The component of the plasma membrane that acts as the selective barrier for diffusion is the integral proteins.

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