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Protein synthesis begins with the amino acid ___________ as its codon is the one used as the "start codon" by nearly all organisms.


A) methionine
B) arginine
C) cysteine
D) leucine

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A mutation that changes a codon that originally coded for an amino acid into a stop codon is called a


A) frameshift mutation.
B) missense mutation.
C) silent mutation.
D) nonsense mutation.

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Mutations that result in much less of a protein or a protein with limited function are known as


A) null mutations.
B) hypomorphic mutations.
C) hypermorphic mutations.
D) conditional mutations.
E) neomorphic mutations. Blooms Level 2: Understand

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Assume that for a given gene a mutation creates an allele that functions as a dominant negative.The gene codes for a protein that forms a trimer within the cell.If at least one of the subunits has the mutant structure the entire protein is inactivated.For a heterozygous individual, what percent of the trimers present in the cell will be inactive?


A) 100%
B) 25%
C) 50%
D) 6.25%
E) 12.5%
Blooms Level 4: Analyze

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Which of the following statements is true under ordinary conditions?


A) DNA and RNA last only for a short time within a cell.
B) DNA lasts forever within a cell while RNA lasts only for a short time.
C) RNA lasts forever within a cell while DNA lasts only for a short time.
D) RNA and DNA both last forever within a cell.

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How many different amino acids could be coded for using the synthetic mRNA sequence of (5' UGCUGCUGC 3') ?


A) 0
B) 1
C) 2
D) 3

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Transcription occurs in the ________ and translation occurs in the __________ of prokaryotic cells.


A) nucleus, cytoplasm
B) cytoplasm, nucleus
C) nucleus, nucleus
D) cytoplasm, cytoplasm

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Which of these is NOT a character of the genetic code?


A) There are the same number of codons as there are amino acids.
B) The code is used by nearly every living organism.
C) Some amino acids have multiple codons.
D) The code is degenerate.

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Mutations that abolish the function encoded by the wild-type allele are known as


A) null mutations.
B) hypomorphic mutations.
C) hypermorphic mutations.
D) conditional mutations.
E) neomorphic mutations. Blooms Level 2: Understand

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An anticodon is a physical component of a/an _______ molecule.


A) tRNA
B) mRNA
C) rRNA
D) DNA

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A bacterial (prokaryotic) ribosome is composed of ______ subunits.


A) 20S and 40S
B) 30S and 50S
C) 40S and 60S
D) 50S and 70S

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A mutation that occurs when a base is inserted into or deleted from a DNA sequence, completely altering the subsequent amino acid sequence, is called a


A) frameshift mutation.
B) missense mutation.
C) silent mutation.
D) nonsense mutation.

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The (expressed) sequences within mRNA that code for gene products are called


A) extremes.
B) exons.
C) inclusions.
D) introns.

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The sequences within mRNA that are spliced out (removed) are called


A) extremes.
B) exons.
C) inclusions.
D) introns.

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A neomorphic dominant mutation in the Antennapedia (Antp) gene of Drosophila causes


A) kinks to form in their tails.
B) shortened tails.
C) total loss of color vision.
D) failure to assemble microtubules during mitosis.
E) growth of a leg from the head region. Blooms Level 2: Understand

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Which enzyme forms peptide bonds between adjacent amino acids during polypeptide synthesis?


A) RNA polymerase
B) phosphotransferase
C) peptidyl transferase
D) ribonuclease

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There are ______________ usually found in the genetic code.


A) 3 start codons and 1 stop codon
B) 2 start codons and 2 stop codons
C) 1 start codon and 3 stop codons
D) 0 start codons and 4 stop codons

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Which of these is NOT a step in transcription?


A) replication
B) initiation
C) termination
D) elongation

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The appearance of a novel phenotype resulting from the substitution of a single base pair might be due to


A) change in the amino acid sequence only.
B) change in the amount of protein expressed.
C) alteration in a gene that codes for a nontranslated RNA.
D) change in the developmental time or location at which a gene is expressed.
E) All of the choices are possible consequences of a single base pair substitution. Blooms Level 3: Apply

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A(n) _____________ consists of proteins and small nuclear RNAs forming discrete particles that mediate splicing.


A) holoenzyme
B) splicesome
C) nucleosome
D) ribosome
E) chromosome
Blooms Level 1: Remember

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