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Viruses attach to their hosts via ________.


A) host glycoproteins
B) host phospholipids
C) viral phospholipids
D) viral flagella
E) All of the choices are correct

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A common method for cultivating viruses in the lab is to use in vitro systems called ________ cultures.


A) embryo
B) cell
C) plaque
D) bacteriophage
E) egg

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Viruses are ultramicroscopic because they range in size from 2 mm to 450 mm.

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An RN in a pediatric emergency department performs a triage patient on a 13-month-old male. The patient's father states he had difficulty waking his son from a nap that afternoon. Additionally, the infant had difficulty crawling and had difficulty with feeding the following morning. The RN observes that the patient has a weak cry. Upon further assessment, the patient's father noted that the infant had ingested fresh honey on his toast at breakfast yesterday. The medical team suspects Clostridium botulinum infection due to the ingestion of bacterial endospores. -Even though it is a bacterium,Clostridium botulinum can be made more pathogenic once infected with a(n) ________.


A) bacteriophage
B) oncogene
C) plaque
D) retrovirus

Correct Answer

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Oncoviruses include all the following except ________.


A) hepatitis B virus
B) measles virus
C) papillomavirus
D) HTLV I
E) Epstein-Barr virus

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Which of the following is not a characteristic of a transformed cell?


A) Viral nucleic acid integrated into host DNA
B) Decreased growth rate
C) Alterations in chromosomes
D) Changes in cell surface molecules
E) Capacity to divide indefinitely

Correct Answer

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You are running an experiment in calf serum,which cannot be autoclaved because proteins essential to your protocol will be denatured.  You decide to filter sterilize the serum since the 0.22μm filter is small enough to block any bacteria that may contaminate your tissue culture.  The success of this procedure hinges on the fact that ________.


A) the presence of viruses in your serum is inconsequential to your experiment
B) some of the bacteria will still be allowed to filter through
C) viruses,as well as bacteria,will also be blocked by the 0.22μm pore size
D) the proteins in the serum are also blocked by the pore size

Correct Answer

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What structures are used by bacteriophages to attach to host cell receptors?


A) Sheath
B) Tail fibers
C) Nucleic acid
D) Capsid head
E) None of the choices are correct

Correct Answer

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An ideal antiviral drug would be one that killed the host cell,effectively preventing the virus from replicating.

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False

The development of antiviral drug therapy is difficult because ________.


A) viruses are obligate intracellular parasites so the host cell can be harmed by the drug
B) viruses do not have specific replication cycles that can be targeted
C) viruses do not contain genetic material
D) their life cycles do not have distinctive stages

Correct Answer

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When a bacterium acquires a trait from its temperate phage,it is called ________.


A) transformation
B) lysogenic conversion
C) viral persistence
D) transcription
E) translation

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Which of the following will not support viral cultivation?


A) Live lab animals
B) Embryonated bird eggs
C) Primary cell cultures
D) Continuous cell cultures
E) All of the choices will support viral cultivation.

Correct Answer

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Respiratory syncytial virus (RSV) is a common respiratory virus that causes mild cold-like symptoms in most individuals,but can be more serious in infants and the elderly.RSV is so-named because ________.


A) it causes the fusion of damaged host cells,forming a large,multinucleated cell
B) it causes the proliferation of inclusion bodies within the host cell
C) it causes a persistent infection in the host
D) it transforms the host cell,causing cancer

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Viruses are unable to multiply outside of a host cell.

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When a virus enters a host cell,the viral genes redirect the genetic and metabolic activities of the host cell.

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One of the principal capsid shapes is a 20-sided figure with 12 evenly spaced corners referred to as a(n) ________ capsid.


A) spiked
B) complex
C) icosahedral
D) helical
E) buckeyball

Correct Answer

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Viral nucleic acids include which of the following?


A) Double-stranded DNA
B) Single-stranded DNA
C) Double-stranded RNA
D) Single-stranded RNA
E) All of the choices are correct

Correct Answer

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E

T-even phages ________.


A) include the poxviruses
B) infect Escherichia coli cells
C) enter host cells by engulfment
D) have helical capsids
E) All of the choices are correct

Correct Answer

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Uncoating of viral nucleic acid ________.


A) does not occur in bacteriophage multiplication
B) involves enzymatic destruction of the capsid
C) releases viral nucleic acid into the cell
D) occurs before replication
E) All of the choices are correct

Correct Answer

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The primary purpose of viral cultivation is ________.


A) to isolate and identify viruses in clinical specimens
B) to prepare viruses for vaccines
C) to do detailed research on viral structure,lifestyle,genetics,and effects on host cells
D) All of the choices are correct

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D

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