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At an excitatory chemical synapse between two neurons


A) there is increased permeability of the postsynaptic cell to both Na⁺ and K⁺.
B) a small hyperpolarization of the postsynaptic membrane occurs when the synapse is activated.
C) an action potential in the presynaptic neuron always causes an action potential in the postsynaptic neuron.
D) excitation occurs because K⁺ enters the postsynaptic cell.
E) action potentials spread through gap junctions between cells.

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The basal nuclei are important subcortical nuclei in the cerebrum.

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If a graded potential on a dendrite results in a 5mV depolarization,the depolarization at the axon hillock of the axon might be less than 5mV.

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Acetylcholine is the main neurotransmitter released by


A) preganglionic sympathetic neurons and cells of the adrenal medulla.
B) cells of the adrenal medulla and postganglionic parasympathetic neurons.
C) motor neurons and postganglionic sympathetic neurons.
D) preganglionic sympathetic neurons and postganglionic sympathetic neurons.
E) preganglionic sympathetic neurons and motor neurons.

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During which of the following phases is K⁺ permeability greater than at rest?


A) During the after-hyperpolarization phase of an AP
B) During vesicular release of neurotransmitter from the presynaptic neuron
C) During the repolarizing phase of an AP
D) During the depolarizating phase of an AP
E) None of these,K⁺ permeability is greatest at rest

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Dorsal root ganglia contain the cell bodies of efferent neurons.

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The regions of myelinated axon membrane that have the highest permeability to ions are the


A) ganglia.
B) nodes of Ranvier.
C) synaptic membranes.
D) glial cells.
E) pia mater.

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The sympathetic division of the autonomic nervous system is arranged so that it acts largely as a unit,whereas the components of the parasympathetic division generally act as discrete, independent components.

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The portion of the peripheral nervous system that is composed of nerve fibers that innervate skeletal muscle is called the


A) afferent nervous system.
B) sympathetic nervous system.
C) parasympathetic nervous system.
D) somatic motor nervous system.
E) autonomic nervous system.

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Which best describes temporal summation?


A) A synapse is stimulated a second time before the effect of a first stimulus at the synapse has terminated.
B) It only refers to addition of EPSPs.
C) Two synapses on different regions of a cell are stimulated at the same time.
D) It always brings a postsynaptic cell to threshold.
E) The size of an EPSP depends on the size of the stimulus.

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Inside a neuron,calcium binding sites are likely found on


A) smooth endoplasmic reticulum.
B) kinesin proteins.
C) proteins associated with synaptic vesicles.
D) dyenin proteins.
E) lysosomal proteins.

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Which of the following kinds of neurons are NOT generally cholinergic?


A) Somatic motor neurons
B) Postganglionic sympathetic neurons
C) Postganglionic parasympathetic neurons
D) Preganglionic sympathetic neurons
E) Preganglionic parasympathetic neurons

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Which of the following statements about EPSPs is FALSE?


A) They are produced by the opening of ligand-gated sodium channels.
B) They transmit signals over relatively short distances.
C) They depolarize postsynaptic cell membranes.
D) They are able to summate.
E) They are always the same amplitude.

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Neuronal axons typically have abundant


A) voltage-gated channels for Na⁺ that open in response to depolarization.
B) voltage-gated channels for K⁺ that open in response to hyperpolarization.
C) ligand-gated channels for Na⁺.
D) ligand-gated channels for K⁺.
E) voltage-gated channels for Ca²⁺.

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Which describes the response of the voltage-gated channels when an axon is stimulated to threshold?


A) K⁺ channels open before the Na⁺ channels.
B) Na⁺ channels are activated and then inactivated.
C) K⁺ channels open at the same time as the Na⁺ channels.
D) K⁺ channels are opened when Na⁺ binds to the channel.
E) K⁺ influx causes Na⁺ channels to inactivate.

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Which of the following statements concerning the properties of action potentials is TRUE?


A) The rate of propagation of an action potential down an axon is independent of stimulus strength.
B) Action potentials can undergo summation.
C) A supra-threshold stimulus can stimulate an action potential during the absolute refractory period.
D) Action potentials generally propagate from the axon terminal toward the axon hillock.
E) Increasing the size of a stimulus will increase the amplitude of an action potential.

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The lipid portion of a cell's plasma membrane constitutes a barrier to current.

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Postganglionic neuron cell bodies of the autonomic nervous system have which category of neurotransmitter receptor?


A) Adrenergic receptors
B) Serotonin receptors
C) Muscarinic acetylcholine receptors
D) Nicotinic acetylcholine receptors
E) Dopamine receptors

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Which is one of the most abundant excitatory neurotransmitters in the CNS?


A) Glutamate
B) Dopamine
C) Norepinephrine
D) Gamma-aminobutyric acid (GABA)
E) Endorphin

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You are studying the role of a newly discovered neurotransmitter.  You find that there are receptors for this neurotransmitter on interneurons in the brain and that when it binds,it causes the opening of K⁺ channels.  What can we expect of the postsynaptic cells under influence of this neurostransmitter?


A) The postsynaptic cell will immediately undergo an action potential.
B) The postsynaptic cell will undergo an IPSP.
C) The postsynaptic cell will undergo an EPSP.
D) There will be no change to the membrane potential in the postsynaptic cell.

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