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Which of the following is TRUE about the concentration gradient of Na⁺ in a neuron at rest?


A) It favors its movement into the cell at the resting membrane potential.
B) It favors its movement out of the cell at the resting membrane potential.
C) It is equal and opposite to the electrical potential acting on Na⁺ at the resting membrane potential.
D) It is in the same direction as the diffusion potential due to the concentration gradient for K⁺.
E) It favors movement of Na⁺ in the opposite direction as the electrical potential acting on Na⁺ at the resting membrane potential.

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Which is TRUE about neuronal membrane electrical and concentration gradients at the peak of the action potential?


A) The electrical gradient is in a direction that would tend to move K⁺ out of the cell.
B) The concentration gradient for K⁺ is in a direction that would tend to move it into the cell.
C) The concentration gradient for K⁺ greatly increases compared to at rest.
D) The concentration gradient for Na⁺ is in a direction that would tend to move it out of the cell.
E) The electrical gradient for Na⁺ is in a direction that would tend to move it into the cell.

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Excessive alcohol intake can cause difficulty maintaining posture and coordinating body movements.This is likely due to alcohol's effect stimulatory effect on GABA-releasing neurons in the


A) cerebellum.
B) diencephalon.
C) medulla oblongata.
D) eyes.
E) cerebrum.

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Which is FALSE about interneurons?


A) They receive synaptic input from other neurons in the CNS.
B) They sum excitatory and inhibitory synaptic inputs.
C) They deliver synaptic input on other neurons. 
D) They make synapses on effector organs in the PNS.
E) They can transmit information between afferent neurons and efferent neurons. 

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The central nervous system includes the


A) afferent nerves and spinal cord.
B) efferent nerves and spinal cord.
C) autonomic nervous system and the brain.
D) brain stem and the autonomic nervous system.
E) brain and spinal cord.

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Which of the following statements about the refractory period of a membrane is TRUE?


A) The absolute refractory period refers to the period of time during which another action potential cannot be initiated in that part of the membrane that is undergoing an action potential,no matter how great the strength of the stimulus.
B) The relative refractory period refers to the period of time during which another action potential can be initiated in that part of the membrane that has just undergone an action potential if a stronger than normal stimulus is applied.
C) The refractory period prevents the action potential from spreading back over the part of the membrane that just underwent an action potential.
D) The refractory period places an upper limit on the frequency with which a nerve cell can conduct action potentials.
E) All of the answer choices are correct.

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Which is NOT an example of a graded potential?


A) A receptor potential in a sensory receptor cell
B) A depolarizing excitatory postsynaptic potential (EPSP)
C) A hyperpolarizing inhibitory postsynaptic potential (IPSP)
D) A depolarizing pacemaker potential
E) A depolarizing action potential

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In clinical trials,scientists discover that use of drug X results in a decrease in norepinephrine signaling.In the process of making a list of possible mechanisms of this drug to test,which of the following is NOT a plausible explanation for the effects of drug X?


A) X inhibits synthesis of norepinephrine at the axon terminal.
B) X inhibits norepinephrine release from the terminal.
C) X blocks reuptake of norepinephrine by the terminal.
D) X is an adrenergic receptor antagonist.
E) X stimulates the catabolism of norepinephrine.

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Which is TRUE about the resting membrane potential?


A) It requires very few ions to be distributed unevenly.
B) It has the same value in all cells.
C) It is oriented so that the cell's interior is positive with respect to the extracellular fluid.
D) Only nerve and muscle cells have a potential difference across the membrane at rest.
E) It is not altered by changing concentration gradients of permeating ions.

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A presynaptic (axo-axonal) synapse


A) is a synapse between an axon terminal and a dendrite that can be either excitatory or inhibitory.
B) is a synapse between an axon terminal and another axon's terminal that can be either excitatory or inhibitory.
C) is any synapse onto a cell body,and they can be either stimulatory or inhibitory.
D) is a synapse between an axon terminal and a dendrite of the same cell,which is always inhibitory.
E) is a synapse between an axon terminal and another axon's terminal that is always inhibitory.

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Visual signals travel on myelinated axons.While most pain signals travel on unmyelinated axons.  If you get a paper cut,will you see the cut happen or feel the pain first?


A) Both sensations will occur at the same time.
B) You will feel the pain sensation before the visual sensation.
C) You will experience the visual sensation before the pain sensation.
D) It depends on the magnitude of the pain sensation,it may reach the brain first or second.

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Which of the following statements about norepinephrine is FALSE?


A) Norepinephrine is a neurotransmitter.
B) Norepinephrine binds to adrenergic receptors.
C) Norepinephrine is a catecholamine. 
D) Dopamine is a precursor to norepinephrine.
E) Epinephrine is a precursor to norepinephrine.

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The cerebrum consists only of gray matter.

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Which of the following statements regarding action potentials generated in a neuronal membrane is FALSE?


A) Action potentials travel in both directions along the axon.
B) An action potential generates a new action potential in an adjacent area of membrane.
C) An action potential generates a local current that depolarizes adjacent membrane to threshold potential.
D) Action potentials are usually initiated at the axon hillock of a neuron.
E) An action potential generated by a threshold stimulus is the same size as one generated by a supra-threshold stimulus.

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Neuron X makes inhibitory axon-axonal synaptic contact with neuron Y at the synapse of Y and neuron Z.Which will occur when action potentials are stimulated in neuron X?


A) Neuron Y will be inhibited from reaching the threshold to fire an action potential.
B) The release of neurotransmitter by neuron Y will be inhibited.
C) The synapse between neurons Y and Z will be changed from an excitatory synapse to an inhibitory one.
D) Neurons Y and Z will both be more likely to reach threshold and fire an action potential.
E) Neurons Y and Z will both be less likely to reach threshold and fire an action potential.

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Two neighboring neurons are at rest.  Neuron A has a resting membrane potential of -80mV,Neuron B has a resting membrane potential of -70mV. Which is likely to be TRUE?


A) Neuron A has more K⁺ channels open than Neuron B.
B) Neuron B has more K⁺ channels open than Neuron A.
C) Neuron A has more Na⁺ channels open than Neuron B.
D) Neuron B has more Na⁺ channels open than Neuron A.
E) None of the answer choices are correct.

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SNARE receptor protein complexes in presynaptic neurons function as inhibitors of calcium transport to dampen or reduce the amount of neurotransmitter vesicles that participate in exocytosis.

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The membrane potential of most neurons at rest is


A) equal to the equilibrium potential for potassium.
B) equal to the equilibrium potential for sodium.
C) slightly more negative than the equilibrium potential of potassium ion.
D) more positive than the equilibrium potential for potassium.
E) more positive than the equilibrium potential for sodium.

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The relative refractory period of an excitable membrane refers to the period of time during which no stimulus,however strong,will elicit a second action potential in the membrane.

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The fire alarm in your building is sounding off and you are hurriedly collecting your belongings before evacuating.  Which portion of the nervous system is dominant?


A) Afferent nervous system
B) Sympathetic nervous system
C) Parasympathetic nervous system
D) Somatic motor nervous system
E) Autonomic nervous system

Correct Answer

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