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One of the most common causes of acute tubular necrosis (ATN) is


A) ischemic conditions.
B) cytotoxic agents.
C) immune reaction.
D) prolonged postrenal kidney injury.

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The effect on the renal tubules during the postoliguric phase of acute tubular necrosis involves


A) reconstruction of the basement membrane.
B) blocking the tubule lumens by dead cells.
C) making the glomeruli patent again.
D) regeneration of the renal tubular epithelium.

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If acute tubular necrosis (ATN) does not resolve and continued tubular dysfunction ensues, the patient will then experience


A) oliguria and sodium retention.
B) infections and sepsis.
C) magnesium and phosphorus loss in urine.
D) polyuria and sodium wasting.

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The oliguric phase of acute tubular necrosis is characterized by


A) fluid excess and electrolyte imbalance.
B) fever and diminishing cognition.
C) sodium retention and potassium loss in the urine.
D) magnesium and phosphorous loss in the urine.

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Prerenal acute kidney injury may be caused by


A) severe hypotension.
B) glomerulonephritis.
C) bilateral kidney stones.
D) acute tubular necrosis.

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In patients with polycystic kidney disease, renal failure is expected to progress over time as the cystic process destroys more nephrons.At what point will a patient reach end-stage renal disease?


A) Greater than 15%
B) Greater than 25% nephron loss
C) Greater than 50% nephron loss
D) Greater than 90% nephron loss

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Anemia in people who have end-stage chronic renal disease is caused by


A) chronic loss of blood in the urine.
B) poor appetite, with lack of iron intake.
C) decreased secretion of erythropoietin.
D) increased secretion of aldosterone.

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The condition associated with end-stage chronic renal disease that is the most immediately life threatening is


A) azotemia.
B) increased creatinine.
C) hypertension.
D) hyperkalemia.

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Individuals with end-stage chronic renal disease are at risk for renal osteodystrophy and spontaneous bone fractures, because


A) excess potassium leaches calcium from bone.
B) erythropoietin secretion is impaired.
C) urea causes demineralization of bone.
D) they are deficient in active vitamin D.

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Appropriate management of end-stage renal disease includes


A) potassium supplementation.
B) a high-protein diet.
C) erythropoietin administration.
D) a high-phosphate diet.

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Postrenal acute kidney injury may be caused by


A) severe hypotension.
B) glomerulonephritis.
C) bilateral kidney stones.
D) acute tubular necrosis.

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Osteoporosis commonly occurs in patients with end-stage renal disease because of


A) hyperparathyroidism.
B) hypercalcemia.
C) excess active vitamin D.
D) phosphorous deficiency.

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The risk for contrast media-induced acute tubular necrosis (ATN) is highest in


A) a 70-year-old patient with heart failure.
B) a 50-year-old patient post gallbladder surgery.
C) a 12-year-old patient with recurrent bladder infections.
D) a 30-year-old patient with appendicitis.

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Gastrointestinal drainage, perioperative and postoperative hypotension, and hemorrhage may all contribute to renal failure by causing


A) hydronephrosis.
B) acute tubular necrosis.
C) nephrosis.
D) renal inflammation.

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Which intervention has been found to retard the advancement of chronic kidney disease?


A) Calcium supplementation
B) Erythropoietin
C) Insulin
D) ACE inhibitors

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The patient most at risk for post-renal acute kidney injury is a(n)


A) elderly patient with hypertrophy of the prostate.
B) middle-aged woman with bladder infection.
C) young child with reflux at the ureterovesical junction.
D) patient who has both hypertension and diabetes.

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The most common agent resulting in nephrotoxicity and subsequent acute tubular necrosis (ATN) in hospitalized patients is


A) contrast media.
B) antibiotics.
C) cancer chemotherapy.
D) recreational drugs.

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Acute tubular necrosis can occur from


A) increased ammonia levels from liver failure.
B) contrast dyes used for radiologic studies.
C) ischemia due to hypovolemia.
D) antibiotics that are nephrotoxic.

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