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Use the following information to answer the questions below. A research team established similar lymphocyte cultures from a number of human donors,including healthy teenagers of both genders,patients already suffering from long-term bacterial infections,and elderly volunteers.They found that the increase in lymphocyte incorporation after pathogen introduction was slightly lower in some of the female teenagers and significantly lower in each of the elderly persons.They repeated the study with a larger number of samples but got the same results. -Which of the following investigations might be most productive to show what the data on the teenagers might indicate?


A) test male teenagers
B) test teenagers who say they are not sexually active
C) test female teens at different times in their menstrual cycles
D) test relatives of the teens previously tested
E) test teenagers from different school systems

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Use the data in the table below to answer the following questions. The data were obtained from a study of the length of time spent in each phase of the cell cycle by cells of three eukaryotic organisms designated beta,delta,and gamma. Use the data in the table below to answer the following questions. The data were obtained from a study of the length of time spent in each phase of the cell cycle by cells of three eukaryotic organisms designated beta,delta,and gamma.     Minutes Spent in Cell Cycle Phases -The best conclusion concerning delta is that the cells A) contain no DNA. B) contain no RNA. C) contain only one chromosome that is very short. D) are actually in the G₀ phase. E) divide in the G₁ phase. Minutes Spent in Cell Cycle Phases -The best conclusion concerning delta is that the cells


A) contain no DNA.
B) contain no RNA.
C) contain only one chromosome that is very short.
D) are actually in the G₀ phase.
E) divide in the G₁ phase.

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For a chemotherapeutic drug to be useful for treating cancer cells,which of the following is most desirable?


A) It is safe enough to limit all apoptosis.
B) It does not alter metabolically active cells.
C) It only attacks cells that are density dependent.
D) It interferes with cells entering G₀.
E) It interferes with rapidly dividing cells.

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Which of the following triggers the cell's passage past the G₂ checkpoint into mitosis?


A) PDGF
B) MPF
C) protein kinase
D) cyclin
E) Cdk

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Which of the following is (are) required for motor proteins to function in the movement of chromosomes toward the poles of the mitotic spindle?


A) intact centromeres
B) an MTOC (microtubule organizing center)
C) a kinetochore attached to the metaphase plate
D) ATP as an energy source
E) synthesis of cohesin

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Use the following information to answer the questions below. A student is looking through his light microscope (~450 X) at a squashed and stained onion root tip.Some,but not all,of the cells have clearly visible chromosome strands. -When the cell has just completed telophase,which of the following does he see?


A) a clear area in the centre of the cell
B) chromosomes clustered at the poles
C) individual chromatids separating
D) formation of vesicles at the midline
E) two small cells with chromatin

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The following questions are based on the following figure. The following questions are based on the following figure.    -MPF reaches its threshold concentration at the end of this stage. A) I B) II C) III D) IV E) V -MPF reaches its threshold concentration at the end of this stage.


A) I
B) II
C) III
D) IV
E) V

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All cell cycle checkpoints are similar in which way?


A) They respond to the same cyclins.
B) They utilize the same Cdks.
C) They give the go-ahead signal to progress to the next checkpoint.
D) They each have only one cyclin/Cdk complex.
E) They activate or inactivate other proteins.

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A mutation results in a cell that no longer produces a normal protein kinase for the M phase checkpoint.Which of the following would likely be the immediate result of this mutation?


A) The cell would prematurely enter anaphase.
B) The cell would never leave metaphase.
C) The cell would never enter metaphase.
D) The cell would never enter prophase.
E) The cell would undergo normal mitosis, but fail to enter the next G₁ phase.

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E

Which of the following describe(s) cyclin-dependent kinase (Cdk) ?


A) Cdk is inactive, or "turned off," in the presence of cyclin.
B) Cdk is present throughout the cell cycle.
C) Cdk is an enzyme that attaches phosphate groups to other proteins.
D) Cdk is inactive, or "turned off," in the presence of cyclin and it is present throughout the cell cycle.
E) Cdk is present throughout the cell cycle and is an enzyme that attaches phosphate groups to other proteins.

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Use the following information to answer the questions below. A research team established similar lymphocyte cultures from a number of human donors,including healthy teenagers of both genders,patients already suffering from long-term bacterial infections,and elderly volunteers.They found that the increase in lymphocyte incorporation after pathogen introduction was slightly lower in some of the female teenagers and significantly lower in each of the elderly persons.They repeated the study with a larger number of samples but got the same results. -What might be among the research team's conclusions?


A) The young women showed these results because they have poorer nutrition.
B) The elderly persons' samples demonstrated their lowered immune responses.
C) The young men had higher responses because they are generally healthier.
D) The patient samples should have had the lowest response but did not, so the experiment is invalid.
E) The elderly donor samples represent cells no longer capable of any cell division.

Correct Answer

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The drug cytochalasin B blocks the function of actin.Which of the following aspects of the cell cycle would be most disrupted by cytochalasin B?


A) spindle formation
B) spindle attachment to kinetochores
C) DNA synthesis
D) cell elongation during anaphase
E) cleavage furrow formation and cytokinesis

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If there are 20 chromatids in a cell,how many centromeres are there?


A) 10
B) 20
C) 30
D) 40
E) 80

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Starting with a fertilized egg (zygote) ,a series of five cell divisions would produce an early embryo with how many cells?


A) 4
B) 8
C) 16
D) 32
E) 64

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The following information applies to the questions below. Several organisms,primarily protists,have what are called intermediate mitotic organization. -What is the most probable hypothesis about these intermediate forms of cell division?


A) They represent a form of cell reproduction that must have evolved completely separately from those of other organisms.
B) They demonstrate that these species are not closely related to any of the other protists and may well be a different kingdom.
C) They rely on totally different proteins for the processes they undergo.
D) They may be more closely related to plant forms that also have unusual mitosis.
E) They show some but not all of the evolutionary steps toward complete mitosis.

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E

Vinblastine is a standard chemotherapeutic drug used to treat cancer.Because it interferes with the assembly of microtubules,its effectiveness must be related to


A) disruption of mitotic spindle formation.
B) inhibition of regulatory protein phosphorylation.
C) suppression of cyclin production.
D) myosin denaturation and inhibition of cleavage furrow formation.
E) inhibition of DNA synthesis.

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You have the technology necessary to measure each of the following in a sample of animal cells: chlorophylls,organelle density,picograms of DNA,cell wall components,and enzymatic activity.Which would you expect to increase significantly from M to G₁?


A) organelle density and enzymatic activity
B) cell wall components and DNA
C) chlorophyll and cell walls
D) organelle density and cell walls
E) chlorophyll and DNA

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In eukaryotic cells,what are chromosomes are composed of?


A) DNA and RNA
B) DNA only
C) DNA and proteins
D) DNA and phospholipids
E) DNA, proteins and phospholipids

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The following questions are based on the following figure. The following questions are based on the following figure.    -In the figure above,mitosis is represented by which numbered part(s) of the cycle? A) I B) II C) III D) IV E) V -In the figure above,mitosis is represented by which numbered part(s) of the cycle?


A) I
B) II
C) III
D) IV
E) V

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Taxol is an anticancer drug extracted from the Pacific yew tree.In animal cells,Taxol disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor,tubulin.Surprisingly,this stops mitosis.Specifically,Taxol must affect


A) the formation of the mitotic spindle.
B) anaphase.
C) formation of the centrioles.
D) chromatid assembly.
E) the S phase of the cell cycle.

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A

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