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Exam 6: Rh Blood Group System

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Question 1

Multiple Choice

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A patient phenotypes as D+C+E-c-e+.Predict the most likely genotype.

A) R^₁r
B) R^₁R^₁
C) R^₁r'
D) R^₁R^₀

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B

Question 2

Multiple Choice

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The inheritance of the Rh antigens are:

A) X-linked recessive.
B) X-linked dominant.
C) autosomal recessive.
D) codominant.

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Question 3

Multiple Choice

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The LW antigen expression is typically stronger on _____________ red cells.

An anti-E was identified in a patient who recently received a transfusion.What other Rh system antibody should be investigated?

Which of the following phenotypes will react with anti-f?

The frequency of the D-negative phenotype in the population is:

MATCHING Match the following phenotypes with the most probable genotype in the Weiner nomenclature. -DcE

Anti-D reagent and the D control were tested with patient's red cells.Both tests were 2+ agglutination reactions.What is the interpretation of the results?

Match the Fisher-Race notation with the correct Weiner notation for the following: -r'

All of the following can cause the D antigen expression to be weaker except:

MATCHING Match the following phenotypes with the most probable genotype in the Weiner nomenclature. -DCce

The weak D test detects:

Which of the following is associated with the Rhnᵤll phenotype?

The numeric Rh4 nomenclature refers to which antigen in the Rosenfield notation?

If a D-positive person appears to have anti-D in their serum,what is the most likely explanation?

How would you label a donor who tested negative with anti-D reagent upon immediate-spin and positive in antihuman globulin test?

How is it genetically possible for a child to phenotype as D-negative?

MATCHING Match the following phenotypes with the most probable genotype in the Weiner nomenclature. -DCe

Current theory regarding the genetics of the Rh system suggests that:

An individual's red cells gave the following reactions with antisera: $\begin{array}{|l|l|l|l|l|l|}\hline \text { Anti-D } & \text { Anti-C } & \text { Anti-E } & \text { Anti-c } & \text { Anti-e } & \text { Rh control } \\\hline 4+ & 3+ & 0 & 3+ & 3+ & 0\end{array}$ The most probable genotype is: