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If an operon is regulated by ____ control, genes are ____ by a regulatory protein called a ____. ​


A) positive; on unless they are switched off; repressor
B) negative; off unless they are switched on; repressor
C) negative; on unless they are switched off; repressor
D) positive; off unless they are switched on; repressor
E) positive; on unless they are switched off; activator

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Gene regulation in both prokaryotes and eukaryotes ____. ​


A) involves significant chromatin remodeling
B) requires transcription and translation to occur in separate cellular compartments
C) produces differentiated cells
D) involves transcriptional control
E) involves alternative splicing

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When histones are rearranged to control gene access, it is called ____. ​


A) transcription
B) chromatin remodeling
C) DNA condensation
D) remodeling complex formation
E) acetylation

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Labeling Identify each labeled part in the following illustration of the lac operon. Labeling  Identify each labeled part in the following illustration of the lac operon.   Figure 16.2 Figure 16.2

Premises
Lac repressor
Responses
g
f
b
c
j
d
h
i
e
a
k

Correct Answer

g
f
b
c
j
d
h
i
e
a
k

The genes in an operon are ____. ​


A) each transcribed into individual mRNAs
B) transcribed into a single mRNA transcript
C) controlled by separate promoters
D) transcribed as a single mRNA in prokaryotes, but as individual mRNAs in eukaryotes
E) located at different chromosomal loci

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Labeling Identify each labeled part of the following illustration of eukaryotic DNA. Labeling  Identify each labeled part of the following illustration of eukaryotic DNA.     Figure 16.1 Figure 16.1

Premises
coactivator multiprotein complex
Responses
e
c
f
g
b
d
a

Correct Answer

e
c
f
g
b
d
a

How does RNA polymerase II bind to the DNA? ​


A) It binds directly to the eukaryotic promoter sequence.
B) It binds directly to the TATA box.
C) It binds to transcription factors in the nucleus, and the complex then binds to the promoter.
D) Transcription factors first bind to the promoter, then recruit RNA polymerase II.
E) Some transcription factors bind to the promoter while others bind to RNA polymerase II, then the two groups of proteins bind to each other.

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In prokaryotes, the genes for metabolic pathways are ____. ​


A) always expressed for early steps in the pathway, but generally not expressed for later steps in the pathway
B) always expressed so the bacteria can respond to rapidly to changing conditions
C) turned on and off as conditions change
D) always independently regulated
E) generally expressed at low levels, but expressed at high levels when conditions warrant

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Compare DNA methylation to histone acetylation.

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DNA methylation and histone acetylation ...

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Compare the functions of maternal effect genes, segmentation genes, and homeotic genes in Drosophila . ​

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Maternal effect genes are expressed in t...

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The trp operon is an example of a(n) ____ operon where tryptophan acts as a(n) ____. ​


A) inducible; inducer
B) inducible; activator
C) repressible; corepressor
D) repressible; repressor
E) repressible; inducer

Correct Answer

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In eukaryotes, ____ regulation is the first level at which gene expression is controlled. ​


A) transcriptional
B) translational
C) posttranscriptional
D) posttranslational
E) replicative

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Labeling Identify each labeled part of the following illustration of eukaryotic DNA. Labeling  Identify each labeled part of the following illustration of eukaryotic DNA.     Figure 16.1 Figure 16.1

Premises
proximal promoter region
Responses
d
f
e
c
b
a
g

Correct Answer

d
f
e
c
b
a
g

Changes in pre-mRNA processing and the rate at which mRNAs are degraded are a part of ____. ​


A) histone modifications
B) chromatin remodeling
C) transcriptional regulation
D) posttranscriptional regulation
E) genomic imprinting

Correct Answer

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Transcription factors that control genes for developmental events are encoded by ____ genes. ​


A) Hox
B) homeotic
C) master regulator
D) activator
E) maternal effect

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Explain the difference between benign and malignant tumors. ​

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In benign tumors, the cells have dediffe...

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Labeling Identify each labeled part of the following illustration of eukaryotic DNA. Labeling  Identify each labeled part of the following illustration of eukaryotic DNA.     Figure 16.1 Figure 16.1

Premises
enhancer
Responses
a
e
d
b
c
g
f

Correct Answer

a
e
d
b
c
g
f

Genes expressed in almost all cell types are called ____ genes. ​


A) housekeeping
B) regulated
C) activator
D) homeotic
E) structural

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The default state for the lac operon is "off" while the default state for the trp operon is "on". Explain this difference in regulation and the mechanism of control via the repressor proteins. ​

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The lac operon's function is to allow a ...

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Why is ubiquitin nicknamed the "doom tag"? ​


A) When ubiquitin binds to a target protein, the ubiquitin enzyme degrades the protein.
B) When ubiquitin binds to a target protein, the complex is sent to the proteasome and degraded.
C) If a cell is deficient in ubiquitin, the cell will die.
D) High levels of ubiquitin in a cell cause the cell to destroy vital proteins, leading to premature cell death.
E) Ubiquitin binds to ribosomes and prevents them from translating proteins necessary for cell survival.

Correct Answer

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