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The phenotype of an organism is its set of (genes/traits/chromosomes).

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A(n)(operon/codon/gene)is a specific sequence of nucleotides that codes for a protein or an RNA molecule.

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Compare and contrast the lactose operon with the tryptophan operon.

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Both the lactose and the tryptophan operons have certain features in common.They both contain a set of genes dedicated to a common purpose (such as the catabolism of lactose by the genes of the lactose operon)and regulatory elements such as a promoter and an operator.Each of these operons makes use of a repressor protein,which binds to the operator region and alters the activity of the operon.However,the lactose operon is classified as an inducible operon,which means it requires an inducer (a lactose metabolite)in order to be activated.In the absence of the inducer,the repressor protein shuts down the operon.In contrast,the tryptophan operon is a repressible operon,which requires a corepressor (tryptophan itself)in order to activate the repressor and shut down the operon.In the absence of the corepressor and repressor,the operon is fully functional.In both types of operons,the molecule either catabolized (in the case of lactose)or synthesized (in the case of tryptophan)is an important component of the regulation of the operon.In this way,the cell maintains precise control over these genetic pathways and does not spend time and energy making enzymes that are not needed.For example,making enzymes to catabolize lactose when no lactose is present would waste energy and metabolites.

The horizontal transfer process known as transduction


A) involves a virus.
B) requires a pilus.
C) requires a cell to be "competent."
D) requires a plasmid.
E) involves a mutagen.

F) B) and D)
G) A) and D)

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Typical eukaryotic genomes are composed of ________ chromosomes.


A) multiple linear
B) multiple circular
C) a single circular
D) a single linear
E) both linear and circular

F) A) and D)
G) B) and D)

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A

In generalized transduction,viruses carry random DNA sequences from one cell to another.

A) True
B) False

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The enzyme responsible for separating the DNA strands during DNA replication is (topoisomerase/primase/helicase).

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Which of the following is NOT a characteristic of Okazaki fragments?


A) They are checked for accuracy by DNA polymerase III.
B) They make up the lagging strand of replicated DNA.
C) They begin with an RNA primer.
D) They are joined together by DNA ligase.
E) They are longer in eukaryotic cells.

F) B) and E)
G) B) and D)

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Bacterial strain A contains a plasmid.Bacterial strain B does not.When the bacteria are incubated together in a broth culture strain B cells containing the plasmid can be isolated.Devise an experiment to determine what type of gene transfer process is involved.

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A variety of answers are possible.For ex...

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The chemical 5-bromouracil mimics the chemical structure of thymine,making it a(n)(analog/nucleotide/precursor)of thymine.

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A point mutation can be completely harmless,or it can result in the death of a cell or organism.Explain why these types of mutations can have such varying effects.

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A point mutation is a single base change...

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The (leading/lagging/replicating)strand is the DNA strand that is synthesized continuously during DNA replication.

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Which of the following mechanisms normally repairs pyrimidine dimers?


A) base-excision repair
B) light repair
C) single-strand repair
D) error-prone repair
E) SOS response repair

F) A) and E)
G) None of the above

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The effects of a transposition event are equivalent to a(n)


A) nonsense mutation.
B) missense mutation.
C) frameshift mutation.
D) silent mutation.
E) HFR conjugation.

F) D) and E)
G) A) and C)

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Nucleotide analogs cause frameshift mutations.

A) True
B) False

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Which of the following is a characteristic shared by DNA and RNA polymerases?


A) efficiency of proofreading
B) type of nucleotides used
C) direction of polymerization
D) speed
E) dependence on helicase

F) A) and C)
G) A) and E)

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A codon is a particular combination of three nucleotides.Therefore,there are ________ possible combinations of the nucleotides A,C,G,and T.


A) 16
B) 4
C) 12
D) 64
E) 32

F) A) and B)
G) All of the above

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The phenotype of an organism reflects only part of its genotype.

A) True
B) False

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True

Which of the following causes mutations by creating thymine dimers?


A) nucleotide analogs
B) nitrous acid
C) ultraviolet light
D) benzopyrene
E) gamma rays

F) A) and E)
G) B) and C)

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Genetic elements known as promoters are initiation points in the process of


A) DNA replication.
B) transcription.
C) translation.
D) mutation repair.
E) transformation.

F) All of the above
G) B) and C)

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