A) encode transcription factors that control the expression of genes responsible for specific anatomical structures.
B) are found only in Drosophila and other arthropods.
C) are the only genes that contain the homeobox domain.
D) encode proteins that form anatomical structures in the fly.
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A) Determine the expression pattern for specific human genes.
B) Construct a tree to determine the evolutionary relationships between various bird species.
C) Search for genes that have not yet been identified in eukaryotic genomes.
D) Compare patterns of gene expression in cancerous and non-cancerous cells.
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A) genomics as applied to a species that most typifies the average phenotype of its genus
B) the sequencing of one or two representative genes from several species
C) the sequencing of only the most highly conserved genes in a lineage
D) sequencing DNA from a group of species from the same ecosystem
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A) It is the linkage of each gene to a particular protein.
B) It is the study of the full protein set and its properties.
C) It is the totality of the functional possibilities of a single protein.
D) It is the study of how amino acids are ordered in a protein.
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A) CNVs
B) SNPs
C) STRs
D) Transposable elements
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A) DNA microarray analysis
B) polymerase chain reaction (PCR)
C) DNA sequencing
D) protein-protein interaction assays
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A) The tissue sample shows a high level of gene expression relative to a control (noncancerous) sample.
B) The tissue sample responds to treatment with a mitosis-promoting compound.
C) The mRNAs for the targeted tumor suppressor sequence are not being produced.
D) The mRNAs for cyclins and kinases show unusually high levels of expression.
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A) break genomic DNA at random sites
B) map the position of cloned DNA fragments
C) randomly select DNA primers and hybridize these to random positions of chromosomes in preparation for sequencing
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A) It is due to the large size of eukaryotic proteins.
B) Eukaryotic genomes contain sequences for hard-to-find proteins.
C) There is a high proportion of G-C base pairs in eukaryotic DNA, which makes sequencing difficult to complete.
D) The large size of eukaryotic genomes and the large amount of eukaryotic repetitive DNA make sequencing difficult.
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A) A multigene family includes multiple genes whose products must be coordinately expressed.
B) A multigene family includes genes whose sequences are very similar and that probably arose by duplication.
C) A multigene family includes a gene whose exons can be spliced in a number of different ways.
D) A multigene family includes a highly conserved gene found in a number of different species.
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A) pseudogene creation
B) creation of a gene cluster
C) creation of a polyploid
D) creation of a diploid
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A) splicing of DNA
B) DNA replication
C) meiotic recombination
D) translation
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A) to introduce certain mammoth traits into relatives, such as elephants
B) to clone live woolly mammoths
C) to understand the reasons why mammoths went extinct
D) to better understand the evolutionary relationships among members of related taxa
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A) There should also be persons whose hemoglobin contains two copies of the series of amino acids that is deleted in hemoglobin Lepore.
B) Each of the genes in the hemoglobin gene family must show the same deletion.
C) The deleted gene must have undergone exon shuffling.
D) The deleted region must be located in a different area of the individual's genome.
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A) During evolutionary time, these sequences have separated and have returned to their original positions.
B) DNA sequences within these blocks have become increasingly divergent.
C) Sequences represented have duplicated at least three times.
D) Chromosomal translocations have moved blocks of sequences to other chromosomes.
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A) α1 and ß
B) Αγ and ß
C) α1 and a2
D) α1 and G?
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A) Nonidentical genes produce different versions of globins during development.
B) Pseudogenes interfere with gene expression in adults.
C) The attachment of methyl groups to cytosine following birth changes the type of hemoglobin produced.
D) Histone proteins change shape during embryonic development.
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A) only a pseudogene
B) only a gene with a new function
C) only a gene family with two distinct but related members
D) a pseudogene, a gene with a new function, and a gene family with two distinct but related members
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A) placing them on previously generated genetic maps
B) cloning them into plasmid vectors
C) computer analysis looking for sequence overlaps
D) cloning them into plasmid vectors, placing them on previously generated genetic maps, followed by computer analysis looking for sequence overlaps
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A) Vertebrate genomes can produce more than one polypeptide from a single gene.
B) Vertebrate genomes can produce only one polypeptide from a single gene.
C) Vertebrate genomes are always smaller than other organisms.
D) Alternative splicing leaves introns in vertebrate genes after they are transcribed.
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