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Exam 12: The Cell Cycle

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Question 41

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The following questions are based on Figure 12.3. Figure 12.3 -MPF reaches its threshold concentration at the end of this stage.

A) I
B) II
C) III
D) IV
E) V

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Question 42

Multiple Choice

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A plant-derived protein known as colchicine can be used to poison cells by blocking the formation of the spindle. Which of the following would result if colchicine is added to a sample of cells in G₂?

A) The cells would immediately die.
B) The cells would be unable to begin M and stay in G₂.
C) The chromosomes would coil and shorten but have no spindle to which to attach.
D) The chromosomes would segregate but in a disorderly pattern.
E) Each resultant daughter cell would also be unable to form a spindle.

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Question 43

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Use the data in Table 12.1 to answer the following questions. The data were obtained from a study of the length of time spent in each phase of the cell cycle by cells of three eukaryotic organisms designated beta, delta, and gamma. Table 12.1: Minutes Spent in Cell Cycle Phases -The best conclusion concerning delta is that the cells

The following questions are based on Figure 12.3. Figure 12.3 -At which of the numbered regions would you expect to find cells at metaphase?

Which of the following was a discovery that had to be made before human chromosomes could be correctly counted?

Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cyclin to become catalytically active?

The following questions are based on Figure 12.3. Figure 12.3 -Which number represents the point in the cell cycle during which the chromosomes are replicated?

Starting with a fertilized egg (zygote) , a series of five cell divisions would produce an early embryo with how many cells?

Why do chromosomes coil during mitosis?

Use the following information to answer the questions below. A student is looking through his light microscope (~450 X) at a squashed and stained onion root tip. Some, but not all, of the cells have clearly visible chromosome strands. -When a cell is in anaphase of mitosis, which of the following will he see?

Use the following information to answer the questions below. The research team established similar lymphocyte cultures from a number of human donors, including healthy teenagers of both genders, patients already suffering from long-term bacterial infections, and elderly volunteers. They found that the increase in lymphocyte incorporation after pathogen introduction was slightly lower in some of the female teenagers and significantly lower in each of the elderly persons. They repeated the study with a larger number of samples but got the same results. -What might be among the research team's conclusions?

Which of the following triggers the cell's passage past the G₂ checkpoint into mitosis?

In which group of eukaryotic organisms does the nuclear envelope remain intact during mitosis?

Which of the following is a function of those spindle microtubules that do not attach to kinetochores?

Use the following information to answer the questions below. Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and can therefore be assayed to track their incorporation. In a set of experiments, a student-faculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times. -Which of the following questions might be answered by such a method?

Cells from an advanced malignant tumor most often have very abnormal chromosomes, and often an abnormal total number of chromosomes. Why might this occur?

Where do the microtubules of the spindle originate during mitosis in both plant and animal cells?

Which of the following is true concerning cancer cells?

You have the technology necessary to measure each of the following in a sample of animal cells: chlorophylls, organelle density, picograms of DNA, cell wall components, and enzymatic activity. Which would you expect to increase significantly from M to G₁?