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A negative RNA virus must first ________.


A) synthesize a DNA copy of its genome
B) synthesize a negative RNA copy of its genome
C) synthesize a positive RNA copy of its genome
D) transcribe reverse transcriptase
E) transcribe RNA polymerase

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Which of the following is a true statement regarding lysogeny?


A) Once the phage genome is integrated into the host cell, it remains there permanently.
B) The host bacterial cell acquires new characteristics that are often detrimental to humans.
C) It halts the viral life cycle because the phage genes are no longer replicated.
D) The host bacterial cell is lysed once the phage genome is integrated.

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Mammalian viruses capable of starting tumors are ______.


A) chronic latent viruses
B) oncoviruses
C) syncytia
D) inclusion bodies

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Host cells of viruses include ______.


A) humans and other animals
B) plants and fungi
C) bacteria
D) protozoa and algae
E) All of the choices are correct.

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A naked virus only has a/an ______.


A) capsomere
B) nucleocapsid
C) envelope
D) antigenic surface

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Reverse transcriptase synthesizes ________.


A) a positive RNA strand from a negative RNA strand
B) a negative RNA strand from a positive RNA strand
C) viral RNA from DNA
D) viral DNA from RNA

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Animal viruses have the ability to attach to and enter almost any animal host cell.

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Viruses that infect bacteria are specifically called ______.


A) viroids
B) prions
C) bacteriophages
D) satellite viruses

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How are viroids transmitted?


A) Respiratory secretions
B) Sex
C) Plant seeds
D) Blood products

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Creutzfeldt-Jacob disease is _______.


A) caused by a chronic latent virus
B) initiated by an oncogenic virus
C) caused by a viroid
D) a spongiform encephalopathy of humans
E) also called "mad cow disease"

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Each virus is classified into a genus based on its host, target tissue, and type of disease it causes.

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Who developed a rabies vaccine after realizing the disease was caused by something smaller than a bacterium?


A) Leeuwenhoek
B) Koch
C) Pasteur
D) Cohn
E) Ivanovski

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The correct sequence of events in viral multiplication is ________.


A) penetration, uncoating, synthesis, adsorption, assembly, and release
B) uncoating, penetration, synthesis, assembly, absorption, and release
C) adsorption, penetration, uncoating, synthesis, assembly, and release
D) assembly, synthesis, uncoating, release, penetration, and adsorption
E) adsorption, release, synthesis, uncoating, assembly, and penetration

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In general, most DNA viruses multiply in the host cell's _____, while most RNA viruses multiply in the host cell's _____.


A) nucleus; cytoplasm
B) cytoplasm; cell membrane
C) cell membrane; cytoplasm
D) cytoplasm; nucleus
E) nucleus; endoplasmic reticulum

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The core of every virus particle always contains ______.


A) DNA
B) capsomeres
C) enzymes
D) DNA and RNA
E) either DNA or RNA

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The event that occurs in bacteriophage multiplication that does not occur in animal virus replication is ______.


A) adsorption to the host cells
B) injection of only the viral nucleic acid into the host cell
C) host cell synthesis of viral enzymes and capsid proteins
D) assembly of nucleocapsids
E) replication of viral nucleic acid

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When a bacterium acquires a trait from its temperate phage, it is called ______.


A) transformation
B) lysogenic conversion
C) viral persistence
D) transcription
E) translation

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Which of the following is not a typical capsid shape?


A) Tetrahedral
B) Complex
C) Helical
D) Icosahedron

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Sterilizing filters have a pore size of 0.22 μm. Which of the following statements is true?


A) Bacterial cells are typically between 1-10 μm and pass through the filter, whereas most viruses are between 20 and 200 nm and are therefore blocked.
B) Bacterial cells are typically between 1-10 μm and are blocked by the filter, whereas most viruses are between 20 and 200 nm and therefore pass through.
C) Bacterial cells are typically between 1,000-10,000 nm and pass through the filter, whereas most viruses are between 20 and 200 nm and are therefore blocked.
D) Bacterial cells are typically between 1-10 nm and are blocked by the filter, whereas most viruses are between 20 and 200 μm and therefore pass through.

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Bacteriophages do not undergo adsorption to specific host cell receptors prior to penetration.

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