Question 1

Transfusion of the wrong blood type can cause _______.

Accepted Answer

A)   recipient antibody activation of the complement cascade to attack the RBCs
B)   fever and anemia
C)   systemic shock and kidney failure
D)   massive hemolysis of the donor RBCs
E)   All of the choices are correct.

Question 2

An effective test to determine whether an individual is allergic to a speciﬁc substance is to _______.

Accepted Answer

A)   test for levels of IgE speciﬁc for the allergen
B)   inject high levels of the allergen so see if the patient goes into anaphylactic shock
C)   test for high levels of IgG in the serum
D)   test for the allergen in the blood

Question 3

What will be the immediate action of an allergen when it enters the body for a second time?

Accepted Answer

A)   Binding of allergen to adjacent IgE binding sites on mast cells and basophils
B)   Prostaglandins cause vasodilation and increased vascular permeability
C)   Histamine acts on smooth muscle
D)   Binding of IgE by the Fc region to mast cells and basophils
E)   Degranulation

Question 4

Any heightened immune response resulting in tissue damage is called a/an _______.

Accepted Answer

A)   hypersensitivity
B)   immunodeﬁciency
C)   desensitization
D)   transfusion reaction
E)   autoimmune disease

Question 5

An antihistamine will _______.

Accepted Answer

A)   reverse spasms of respiratory smooth muscles
B)   block synthesis of leukotrienes
C)   inhibit the activity of lymphocytes
D)   bind to histamine receptors on target organs

Question 6

Allergic rhinitis is also known as asthma.

Accepted Answer

A) True 
 B)False

Question 7

All of the following are autoimmune diseases except _______.

Accepted Answer

A)   rheumatoid arthritis
B)   systemic lupus erythematosus
C)   type I diabetes
D)   Graves' disease
E)   metastatic cancer

Question 8

John, a Peace Corps worker in the country of Mali in Africa, was in a car accident while traveling through a rural area. He was treated at a tiny rural hospital, and due to his loss of blood, he required
A transfusion. John has B- blood type and has never received a transfusion before. Which statement
Is correct regarding this scenario?

Accepted Answer

A)   He can be given types O or B, no matter whether Rh- or Rh+. At this point in time, he does not have anti-Rh antibody. O has no antigens on the blood cells, so he is also safe toReceive that type in addition to his own B type.
B)   He can be given A+ blood type in addition to B+. Rh- means that he makes no antibody to Rh.
C)   The preferred blood type to give John, in addition to his own B type blood, would be AB. Both types of blood have the B antigen on the cells, so they would correspond to his ownAntigens. As for Rh, he can receive only Rh- blood since he would have a reaction againstRh+) 
D)   He can safely receive O- blood even though he makes anti-A antibodies.

Question 9

The major category(ies)  of hypersensitivity(ies)  that typically involve(s)  a B-cell immunoglobulin response include(s)  _______.

Accepted Answer

A)   type I only
B)   type I and type IV
C)   type IV only
D)   type I, type II, and type III
E)   type I, type II, type III, and type IV

Question 10

Which event occurs with the sensitizing dose of allergen?

Accepted Answer

A)   Degranulation
B)   Binding of allergen to adjacent IgE binding sites on mast cells and basophils
C)   Binding of IgE by the Fc region to mast cells and basophils
D)   Histamine acting on smooth muscle
E)   Prostaglandins causing vasodilation and increased vascular permeability

Question 11

Bee sting venom is considered to be which type of allergen?

Accepted Answer

A)   Contactant
B)   Inhalant
C)   Injectant
D)   Ingestant

Question 12

Before a type II hypersensitivity can proceed, three immune components must be in place: complement, IgG, and IgM.

Accepted Answer

A) True 
 B)False

Question 13

All of the following represent potential therapy for patients with SCID except _______.

Accepted Answer

A)   graft versus host
B)   transfusion with adensosine deaminase
C)   bone marrow transplants
D)   stem cell grafts
E)   gene therapy

Question 14

A viral infection can lead to the development of type I diabetes.

Accepted Answer

A) True 
 B)False

Question 15

A female who is Rh- _______.

Accepted Answer

A)   is at risk for a pregnancy resulting in hemolytic disease of the newborn
B)   can never have an Rh+ baby
C)   is in the majority of the population with regard to Rh status
D)   inherited two dominant genes

Question 16

What can be a consequence of a genetic deﬁciency in B-cell survival and maturity?

Accepted Answer

A)   Formation of autoantibodies
B)   Host rejection of graft
C)   Graft versus host disease
D)   Hypogammaglobulinemia

Question 17

An example of a secondary acquired immunodeﬁciency is _______.

Accepted Answer

A)   AIDS
B)   adenosine deaminase (AD
A)   deﬁciency
C)   DiGeorge syndrome
D)   agammaglobulinemia
E)   SCID

Question 18

You have dermatitis triggered by a particular material in your socks. Your feet are covered with a really itchy rash, which has developed blisters over the last day or so. You had ?rst worn them two to three days ago, and you did not launder them after buying them at the store. Finding some antihistamine medication in your bathroom cabinet, you decide to take it to relieve the itching rash. Which statement is true?

Accepted Answer

A)   The antihistamine will make the rash worse because it reacts with chemicals release by the lymphocytes in your skin, exacerbating the situation.
B)   The rash will go away because the antihistamine neutralizes the histamine chemicals coming from mast cells in your skin.
C)   The anti-histamine will have no effect on the rash because histamine is not the chemical mediator in this hypersensitivity.
D)   The anti-histamine will have no effect because once a type I hypersensitivity kicks in, it will last for a few days.

Question 19

Corticosteroids will _______.

Accepted Answer

A)   inhibit the activity of lymphocytes
B)   bind to histamine receptors on target organs
C)   block synthesis of leukotrienes
D)   reverse spasms of respiratory smooth muscles

Question 20

Allergic patients receiving small, controlled injections of speciﬁc allergens are undergoing ______.

Accepted Answer

A)   desensitization
B)   tissue matching
C)   degranulation
D)   sensitization

Exam 16: Disorders in Immunity

What can be a consequence of a genetic deﬁciency in B-cell survival and maturity?

Correct Answer
verified

Transfusion of the wrong blood type can cause _______.

Correct Answer
verified

Bee sting venom is considered to be which type of allergen?

Correct Answer
verified

Any heightened immune response resulting in tissue damage is called a/an _______.

Correct Answer
verified

What will be the immediate action of an allergen when it enters the body for a second time?

Correct Answer
verified

An antihistamine will _______.

Correct Answer
verified

Which event occurs with the sensitizing dose of allergen?

Correct Answer
verified

A female who is Rh- _______.

Correct Answer
verified

Before a type II hypersensitivity can proceed, three immune components must be in place: complement, IgG, and IgM.

Correct Answer
verified

All of the following are autoimmune diseases except _______.

Correct Answer
verified

Allergic patients receiving small, controlled injections of speciﬁc allergens are undergoing ______.

Correct Answer
verified

Correct Answer
verified

All of the following represent potential therapy for patients with SCID except _______.

Correct Answer
verified

Corticosteroids will _______.

Correct Answer
verified

Allergic rhinitis is also known as asthma.

Correct Answer
verified

An example of a secondary acquired immunodeﬁciency is _______.

Correct Answer
verified

Correct Answer
verified

A viral infection can lead to the development of type I diabetes.

Correct Answer
verified

An effective test to determine whether an individual is allergic to a speciﬁc substance is to _______.

Correct Answer
verified

The major category(ies) of hypersensitivity(ies) that typically involve(s) a B-cell immunoglobulin response include(s) _______.

Correct Answer
verified

Exam 16: Disorders in Immunity

What can be a consequence of a genetic deﬁciency in B-cell survival and maturity?

Correct AnswerverifiedShow Answer

Transfusion of the wrong blood type can cause _______.

Correct AnswerverifiedShow Answer

Bee sting venom is considered to be which type of allergen?

Correct AnswerverifiedShow Answer

Any heightened immune response resulting in tissue damage is called a/an _______.

Correct AnswerverifiedShow Answer

What will be the immediate action of an allergen when it enters the body for a second time?

Correct AnswerverifiedShow Answer

An antihistamine will _______.

Correct AnswerverifiedShow Answer

Which event occurs with the sensitizing dose of allergen?

Correct AnswerverifiedShow Answer

A female who is Rh- _______.

Correct AnswerverifiedShow Answer

Before a type II hypersensitivity can proceed, three immune components must be in place: complement, IgG, and IgM.

Correct AnswerverifiedShow Answer

All of the following are autoimmune diseases except _______.

Correct AnswerverifiedShow Answer

Allergic patients receiving small, controlled injections of speciﬁc allergens are undergoing ______.

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

All of the following represent potential therapy for patients with SCID except _______.

Correct AnswerverifiedShow Answer

Corticosteroids will _______.

Correct AnswerverifiedShow Answer

Allergic rhinitis is also known as asthma.

Correct AnswerverifiedShow Answer

An example of a secondary acquired immunodeﬁciency is _______.

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

A viral infection can lead to the development of type I diabetes.

Correct AnswerverifiedShow Answer

An effective test to determine whether an individual is allergic to a speciﬁc substance is to _______.

Correct AnswerverifiedShow Answer

The major category(ies) of hypersensitivity(ies) that typically involve(s) a B-cell immunoglobulin response include(s) _______.

Correct AnswerverifiedShow Answer

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