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A patient is admitted for electroconvulsive treatment (ECT). The physician orders the neuromuscular blocking agent succinylcholine to reduce trauma by relaxing skeletal muscles. Explain the process ofmuscle contraction and how a neuromuscular blocking agent such as succinylcholine would interfere with muscle contraction.

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Muscle contraction begins with a stimulu...

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Rigor mortis occurs because ________.


A) sodium ions leak into the muscle causing continued contractions
B) proteins are beginning to break down, thus preventing a flow of calcium ions
C) the cells are dead
D) no ATP is available to release attached actin and myosin molecules

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What is the most distinguishing characteristic of muscle tissue?


A) the ability to respond to nervous stimulation
B) its cells' in ability to reproduce by mitosis
C) the ability to transform chemical energy into mechanical energy to move the body
D) it is composed of multiple cells working together

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What ultimately stops muscle stimulation when the motor neuron ceases firing?

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The ultimate switch is the enzyme acetyl...

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A potential benefit of recruiting slow oxidative fibers for contraction before recruiting fast oxidative and fast glycolytic fibers might be ________.


A) recruiting slow oxidative fibers early helps to tire them out first so that they won't interfere with the more powerful contractions of fast glycolytic fibers
B) because they are slower to respond, slow oxidative fibers must be stimulated first in order to contract simultaneously with the faster fibers
C) this will help to allow for fine control with delicate contractile force with a small stimulus
D) there is little to no benefit from recruiting slow oxidative fibers first and therefore it is in fact fast glycolytic fibers that will be recruited first

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When a muscle fiber contracts, the I bands diminish in size, the H zones disappear, and the Abands do not diminish in length.

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Immediately following the arrival of the stimulus at a skeletal muscle cell there is a shortperiod called the ________ period during which the neurotransmitter is released by exocytosis, diffuses across the synaptic cleft, and binds to its receptors.


A) contraction
B) latent
C) refractory
D) relaxation

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Describe two ways in which the lack of ATP production results in rigor mortis.

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Following the death of an individual, AT...

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The contractile units of skeletal muscles are ________.


A) mitochondria
B) T tubules
C) microtubules
D) myofibrils

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If a muscle fiber were to suddenly and permanently stop producing ATP the fiber would no longer be able to actively transport calcium out of the cytoplasm (sarcoplasm) and theintracellular calcium concentration would rise. Which of the following would you expect to ha ppen?


A) Myosin would be able to bind to the exposed binding sites on thin filaments but it would not be able to detach.
B) Calcium would be transported to the sarcoplasmic reticulum therefore contractions would cease.
C) No change would occur in a muscle that was relaxed to begin with.
D) The fiber would twitch uncontrollably due to excessive calcium bound to troponin.

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Although all the anatomical parts of muscle work together to give it it's characteristics, which of the following proteins listed below would be most associated with the characteristics ofcontractility?


A) potassium (K+) leak channels
B) voltage gated sodium channels
C) thick (myosin) filaments
D) elastic (titin) filaments

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What is the primary function of wave summation?


A) prevent muscle fatigue
B) increase muscle tension
C) produce smooth, continuous muscle contract ion
D) prevent muscle relaxation

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Although there are no sarcomeres, smooth muscle still possesses thick and thin filaments.

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When a sarcomere contracts and thin filaments move over thick filaments you would expect to see ________.


A) the A band to appear darker
B) the I bands to appear wider
C) the H zone to appear wider
D) the I bands to appear smaller

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Which muscle cells have the greatest ability to regenerate?


A) no muscle can regenerate
B) smooth
C) cardiac
D) skeletal

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One of the functions of skeletal muscle contraction is production of heat.

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Myasthenia gravis is a disease that is believed to be caused by autoimmune disorder, resulting in the loss of ACh receptors at the motor end plate of muscle fibers. Which of the following islikely to be a symptom of myasthenia gravis?


A) weakness of muscle
B) coma and loss of voluntary muscle movement
C) dehydration with headache
D) seizures and uncontrollable muscle movement

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During vigorous exercise, there may be insufficient oxygen available to completely break down pyruvic acid for energy. As a result, the pyruvic acid is converted to ________.


A) hydrochloric acid
B) a strong base
C) stearic acid
D) lactic acid

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Peristalsis is characteristic of smooth muscle.

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Although all the anatomical parts of muscle work together to give it it's characteristics, which of the following proteins listed below would be most associated with the characteristics ofextensibility?


A) potassium (K+) leak channels
B) acetylcholine receptors in the motor end plate
C) elastic (titin) filaments
D) thick (myosin) filaments

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