Question 1

Medications administered intravenously can provide much higher effective concentrations than other delivery methods.

Accepted Answer

A) True 
 B)False

Question 2

External infections can be treated by (surface/topical) administration, in which a drug is applied directly to the site of infection.

Accepted Answer

topical

Question 3

The majority of broad spectrum antibacterial medications inhibit (DNA/protein/RNA) synthesis.

Accepted Answer

The answer of The majority of broad spectrum antibacterial medications...

Question 4

Most broad-spectrum antibiotics act by

Accepted Answer

A)   inhibiting protein synthesis.
B)   disrupting the cytoplasmic membrane.
C)   inhibiting metabolic pathways.
D)   inhibiting the synthesis of the cell wall.
E)   inhibiting nucleic acid synthesis. A

Question 5

Some bacteria develop resistance to groups of drugs because the drugs are all structurally similar to each other; this is a phenomenon known as (cross/multiple) resistance.

Accepted Answer

The answer of Some bacteria develop resistance to groups of...

Question 6

Antiviral medications frequently block unique (proteins/enzymes/molecules) to prevent production of new virus.

Accepted Answer

The answer of Antiviral medications frequently block unique (proteins/enzymes/molecules) to...

Question 7

Drugs that slow bacterial growth would be (competitive/synergistic/antagonistic) to penicillin.

Accepted Answer

The answer of Drugs that slow bacterial growth would be...

Question 8

Bacterial DNA replication requires the enzyme gyrase, but eukaryotic replication does not. Ciprofloxacin (ʺCiproʺ)  inhibits gyrase activity. This is an example of

Accepted Answer

A)   selective toxicity.
B)   antimicrobial resistance.
C)   synergism.
D)   use of an analog.
E)   an antimetabolite. A

Question 9

The outer membrane of Gram-negative bacteria enables many antimicrobial drugs to enter the cell more easily.

Accepted Answer

A) True 
 B)False

Question 10

The antimicrobial polymyxin is primarily effective for treating superficial infections with

Accepted Answer

A)   viruses.
B)   fungi.
C)   any bacteria.
D)   Gram-negative bacteria.
E)   Staphylococcus bacteria.

Question 11

Why can microbial resistance to antibiotics and other drugs be considered a primarily genetic phenomenon?

Accepted Answer

Microbial resistance is considered a gen...

Question 12

Several antiviral medications used to treat HIV interfere with

Accepted Answer

A)   protein synthesis.
B)   folic acid synthesis.
C)   cell wall synthesis.
D)   nucleic acid synthesis.
E)   assembly of membranes.

Question 13

Competition between beneficial microbes and potential pathogens is called microbial (synergy/antagonism).

Accepted Answer

The answer of Competition between beneficial microbes and potential pathogens...

Question 14

Which of the following types of antimicrobial agent has the narrowest spectrum of action?

Accepted Answer

A)   azoles
B)   antivirals
C)   sulphonamides
D)   erythromycins
E)   Both azoles and erythromycins have equally narrow spectrums of action.

Question 15

Antimicrobial sugar analogs are effective for

Accepted Answer

A)   preventing bacterial protein synthesis.
B)   preventing nucleic acid synthesis.
C)   preventing cell membrane synthesis.
D)   blocking a metabolic pathway.
E)   preventing virus attachment.

Question 16

Drug-resistant populations of microbes arise when

Accepted Answer

A)   resistant cells become numerous in a population due to their greater vigor.
B)   synergy between medications occurs.
C)   the patient becomes immune to the drug.
D)   exposure to drugs causes mutations that produce resistance.
E)   exposure to drugs selectively kills sensitive cells, allowing overgrowth of resistant cells.

Question 17

Which of the following pathways is specifically inhibited by trimethoprim?

Accepted Answer

A)   the conversion of tetrahydrofolic acid to PABA
B)   the conversion of dihydrofolic acid to tetrahydrofolic acid
C)   the conversion of dihydrofolic acid to PABA
D)   the conversion of PABA to dihydrofolic acid
E)   the conversion of PABA to tetrahydrofolic acid

Question 18

The CDC issued alerts about a bacterial strain known as NDM1 (New Delhi metalo-lactamase 1) . What type of antibiotic resistance is indicated by the name?

Accepted Answer

A)   alteration of the target of the drug
B)   change in the permeability of the drug
C)   inactivation of the drug
D)   overproduction of an enzyme in a key metabolic pathway
E)   removal of the drug via a pump

Question 19

Alterations in the structure of which of the following are an important aspect of Gram -negative bacterial resistance to antimicrobial drugs?

Accepted Answer

A)   plasmids
B)   cytoplasmic membrane
C)   mitochondria
D)   ribosomes
E)   porins

Question 20

Infection of the would be the hardest to treat with antimicrobial drugs.

Accepted Answer

A)   heart
B)   brain
C)   colon
D)   liver
E)   kidneys

Exam 10: Controlling Microbial Growth in the Body: Antimicrobial Drugs

Medications administered intravenously can provide much higher effective concentrations than other delivery methods.

Correct AnswerverifiedShow Answer

External infections can be treated by (surface/topical) administration, in which a drug is applied directly to the site of infection.

Correct Answerverifiedtopical

The majority of broad spectrum antibacterial medications inhibit (DNA/protein/RNA) synthesis.

Correct AnswerverifiedShow Answer

Most broad-spectrum antibiotics act by

Correct AnswerverifiedA

Some bacteria develop resistance to groups of drugs because the drugs are all structurally similar to each other; this is a phenomenon known as (cross/multiple) resistance.

Correct AnswerverifiedShow Answer

Antiviral medications frequently block unique (proteins/enzymes/molecules) to prevent production of new virus.

Correct AnswerverifiedShow Answer

Drugs that slow bacterial growth would be (competitive/synergistic/antagonistic) to penicillin.

Correct AnswerverifiedShow Answer

Bacterial DNA replication requires the enzyme gyrase, but eukaryotic replication does not. Ciprofloxacin (ʺCiproʺ) inhibits gyrase activity. This is an example of

Correct AnswerverifiedA

The outer membrane of Gram-negative bacteria enables many antimicrobial drugs to enter the cell more easily.

Correct AnswerverifiedShow Answer

The antimicrobial polymyxin is primarily effective for treating superficial infections with

Correct AnswerverifiedShow Answer

Why can microbial resistance to antibiotics and other drugs be considered a primarily genetic phenomenon?

Correct AnswerverifiedMicrobial resistance is considered a gen...View AnswerShow Answer

Several antiviral medications used to treat HIV interfere with

Correct AnswerverifiedShow Answer

Competition between beneficial microbes and potential pathogens is called microbial (synergy/antagonism).

Correct AnswerverifiedShow Answer

Which of the following types of antimicrobial agent has the narrowest spectrum of action?

Correct AnswerverifiedShow Answer

Antimicrobial sugar analogs are effective for

Correct AnswerverifiedShow Answer

Drug-resistant populations of microbes arise when

Correct AnswerverifiedShow Answer

Which of the following pathways is specifically inhibited by trimethoprim?

Correct AnswerverifiedShow Answer

The CDC issued alerts about a bacterial strain known as NDM1 (New Delhi metalo-lactamase 1) . What type of antibiotic resistance is indicated by the name?

Correct AnswerverifiedShow Answer

Alterations in the structure of which of the following are an important aspect of Gram -negative bacterial resistance to antimicrobial drugs?

Correct AnswerverifiedShow Answer

Infection of the would be the hardest to treat with antimicrobial drugs.

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified
topical

Correct Answer
verified

Correct Answer
verified
A

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
A

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
Microbial resistance is considered a gen...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified