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Explain how genetic deficiencies of early complement components are associated with immune complex and autoimmune disorders such as systemic lupus erythematosus.

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Complement plays a role in the recogniti...

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The alternate complement activation path and the mannose binding lectin path both function completely independent of antibody.

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All of the following can activate the alternate pathway of complement except


A) mannose.
B) lipopolysaccharides from gram negative bacteria.
C) teichoic acid from gram positive bacteria.
D) certain fungal cell walls.
E) certain parasites.

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Complement activity of the alternate pathway can be assessed using rabbit red blood cells.

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How should specimens be collected and stored if they are to be tested for complement activity?


A) Serum can be refrigerated but not frozen.
B) Serum should be separated from red blood cells.
C) Serum can be stored one to two hours at room temperature prior to testing.
D) All of the above.

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