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Acid- base balance is regulated by a number of systems. Describe the sources of respiratory acidosis and alkalosis as well as metabolic acidosis and alkalosis.

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any alteration in kidney function that r...

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Plasma volume is directly related to blood pressure.

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Antidiuretic hormone binds to receptors on _ cells in the collecting ducts and distal tubules where it .


A) intercalated : causes vesicles with aquaporin- 2 to insert into the basolateral membrane
B) principal : causes insertion of aquaporin- 2 into the apical membrane
C) granular : causes vesicles with aquaporin- 2 to insert into the apical membrane
D) intercalated : causes vesicles with aquaporin- 3 to insert into the apical membrane
E) principal : causes vesicle with aquaporin- 3 to insert into the apical membrane

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Sodium- glucose cotransporters are located where?


A) proximal tubule apical membrane
B) proximal tubule basolateral membrane
C) principal cells basolateral membrane
D) intercalated cells basolateral membrane
E) principal cells apical membrane

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ADH increases the insertion of aquaporin- 2 where?


A) principal cells basolateral membrane
B) principal cells apical membrane
C) intercalated cells basolateral membrane
D) proximal tubule basolateral membrane
E) proximal tubule apical membrane

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During hyperventilation, why do some people detect a tingling sensation in their hands and feet?


A) an increase in carbon dioxide in blood
B) a decrease in carbon dioxide in blood
C) a decrease in blood flow to the distal extremities
D) hyperexcitability of afferent neurons
E) widespread release of catecholamines

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What would the following blood values indicate? Blood pH = 7.3, [HCO3- ] is low, PCO2 is low.


A) respiratory acidosis with renal compensation
B) metabolic alkalosis with respiratory compensation
C) respiratory alkalosis with renal compensation
D) metabolic acidosis with respiratory compensation
E) metabolic acidosis only

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In comparison with the renal cortex, fluid in the proximal tubule is hyperosmotic.

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The maximum osmolarity of urine is 1200 mOsm to 1400 mOsm.

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Respiratory compensation for changes in pH is originated by


A) proprioceptors.
B) central chemoreceptors.
C) baroreceptors.
D) peripheral chemoreceptors.
E) directly affecting the activity of the diaphragm.

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Angiotensin II acts directly in the hypothalamus to stimulate what?


A) a systemic increase in blood pressure
B) an increase in body temperature
C) an increase in thirst
D) the release of aldosterone
E) the release of oxytocin

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Which of the following is a source of water input?


A) digestive tract only
B) renal tubules only
C) metabolism only
D) both digestive tract and metabolism
E) both the digestive tract and renal tubules

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In diabetes insipidus, blood levels of are decreased causing an increase in _ .


A) ADH : plasma volume
B) aldosterone : sodium in the urine
C) insulin : glucose in the urine
D) aldosterone : potassium in the urine
E) ADH : urine volume

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What hormone activates the cAMP second messenger system in principal cells of the distal tubules and collecting ducts?


A) ADH
B) aldosterone
C) angiotensin II
D) atrial natriuretic peptide
E) parathyroid hormone

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