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Assuming resting conditions at sea level, what is the partial pressure of oxygen in systemic arteries?


A) 160 mm Hg
B) 46 mm Hg
C) 40 mm Hg
D) 80 mm Hg
E) 100 mm Hg

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The hydrogen ions released by the dissociation of carbonic acid are buffered by their


A) binding to hemoglobin.
B) active transport out of the erythrocyte.
C) binding to DNA within the nucleus.
D) transport into the erythrocyte as sodium ions move out.
E) transport out of the erythrocyte as a sodium ion moves in.

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Hemoglobin can bind O2, CO2 and H+ all at the same time.

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Which of the following statements about 2,3 -BPG is FALSE?


A) 2,3 -BPG increases the affinity of hemoglobin for oxygen.
B) 2,3 -BPG is produced by red blood cells.
C) 2,3 -BPG is an intermediate of glycolysis.
D) 2,3 -BPG synthesis is inhibited by high levels of oxyhemoglobin.
E) 2,3 -BPG produces a rightward shift in the hemoglobin -oxygen dissociation curve.

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Hyperventilation will cause changes in PCO2 that are detected by the chemoreceptors which causes a(n)


A) decrease in breathing rate and depth of breathing.
B) increase in depth of breathing only.
C) increase in breathing rate and depth of breathing.
D) increase in breathing rate only.
E) decrease in breathing rate only.

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At sea level the air pressure which equals 1 atmosphere is


A) 100 mm Hg.
B) 500 mm Hg.
C) 150 mm Hg.
D) 760 mm Hg.
E) 600 mm Hg.

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A decrease in oxygen -carrying capacity can result from alterations in hemoglobin structure or concentration.

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The partial pressure of an individual gas within a mixture of gases is determined by the total pressure of those gases and the fractional concentration of that gas in the mixture.

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Gangrene is often caused by anaerobic bacteria deep in tissues that lack adequate blood flow and adequate oxygen supply. Many times, gangrene can be treated by putting the patient into a hyperbaric chamber. Which statement best describes why this type of therapy is effective?


A) The increased pressure destroys the cell wall of the bacteria.
B) When the patient is brought back to normal atmospheric pressure, carbon dioxide comes out of solution at high concentrations, which poisons the bacteria.
C) The increased pressure drives nitrogen into the system and nitrogen gas poisons the bacteria.
D) The increased pressure drives more oxygen into the bloodstream and, therefore, anaerobic bacteria cannot survive in the presence of oxygen.
E) The increased pressure creates a higher pressure in the capillaries of the tissue and drives the toxin produced by the bacteria into the bloodstream, where it is diluted.

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There is a substantial safety margin for the uptake of gases in the alveolus because at rest, blood is completely oxygenated after traveling only 1/3 the length of the pulmonary capillary bed.

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Assuming resting conditions at sea level, what is the partial pressure of carbon dioxide in pulmonary veins?


A) 40 mm Hg
B) 160 mm Hg
C) 80 mm Hg
D) 46 mm Hg
E) 100 mm Hg

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The blood in the pulmonary vein is called mixed venous blood.

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Which of the following will increase the unloading of oxygen within the tissue?


A) increased hydrogen ion concentration only
B) increased PCO2 only
C) increased body temperature only
D) both increased hydrogen ion concentration and increased body temperature
E) increased hydrogen ion concentration, increased body temperature, and increased PCO2

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As oxygen binds to hemoglobin, the___________ of the hemoglobin molecule will change through a process of ________such that the binding of oxygen is enhanced.


A) amino acid sequence : phosphorylation
B) affinity : negative cooperativity
C) cooperativity : negativity
D) affinity : positive cooperativity
E) cooperativity : positivity

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Which of the following does NOT contribute to the rapid movement of gases into and out of the blood within the lungs?


A) thin membrane
B) permeability of the membrane
C) rapid blood flow
D) concentration gradient
E) large surface area

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What is an increase in alveolar ventilation to match the demands of increased metabolic activity in the cells called?


A) hyperpnea
B) dyspnea
C) hypoventilation
D) hypopnea
E) hyperventilation

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Chemoreceptors respond primarily to changes in PCO2 indirectly by its effect on


A) 2,3 -diphosphoglycerate (2,3 -DPG) concentration.
B) PO2.
C) hydrogen ion concentration.
D) lactic acid concentration.
E) hemoglobin concentration.

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What percentage of oxygen is transported by hemoglobin?


A) 86%
B) 98.5%
C) 5%
D) 1.5%
E) 75%

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While carbon dioxide is more soluble in solution than oxygen, the amount of carbon dioxide produced by active cells is much greater than can dissolve in solution. Describe the mechanisms by which carbon dioxide is transported to the lungs with particular emphasis on carbon dioxide's binding to hemoglobin and its conversion to bicarbonate.

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In the blood, carbon dioxide is stored i...

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Hyperpnea describes the increase in ventilation that occurs to meet an increase in metabolic demands of the tissues.

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