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The addictive potential of nicotine is comparable to other illicit drugs such as heroin and cocaine.

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Smoking two packs of cigarettes per day for 20 years has been estimated to reduce life expectancy by 14 years.

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Tobacco use in the United States:


A) has increased since the 1950s.
B) remains at 50%.
C) is highest among those that are well educated.
D) is common in people with substance abuse and mental health issues.

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Generally speaking,people that regularly ingest coffee and tea may experience less cognitive deterioration as they grow older.

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The period of withdrawal from nicotine:


A) is typically less than 24 hours.
B) is typically 1 to 2 days.
C) is typically around one week in duration.
D) can persist for several weeks.

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Nicotine impairs cognitive functions such as working memory in nonsmokers.

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The DSM-5 has proposed ______ Caffeine-Related Disorders.


A) 2
B) 3
C) 4
D) 5

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The rewarding effects of nicotine involve:


A) serotonin.
B) acetylcholine.
C) norepinephrine.
D) dopamine.

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Nicotine can improve performance on a variety of cognitive tasks due to acetylcholine.

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Adenosine is a _____ the discharge rate of many central neurons.


A) depressant that increases
B) depressant that decreases
C) stimulant that increases
D) stimulant that decreases

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Caffeinism is:


A) the study of caffeine.
B) the description of the effects of moderate doses of caffeine.
C) the study of people hypersensitive to caffeine.
D) a syndrome produced by the overdose or overuse of caffeine.

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The majority of metabolism of caffeine occurs in:


A) plasma.
B) kidney.
C) liver.
D) bladder.

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Nicotine-induced release of acetylcholine may:


A) improve cognitive performance and arousal.
B) cause adult ADHD.
C) stimulate depression.
D) enhance sensory perception.

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Nicotine withdrawal symptoms occur within about:


A) 15 minutes.
B) 30 minutes.
C) 1 hour.
D) 2 hours.

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The rewarding effects of nicotine involve:


A) nicotinic receptors and the nucleus accumbens.
B) nicotinic receptors on dopamine neurons in the ventral tegmental area and dopamine release onto the nucleus accumbens.
C) glutamate release on neurons in the nucleus accumbens.
D) GABA release onto dopamine neurons in the ventral tegmental area and dopamine release onto the nucleus accumbens.

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The lethal dose of caffeine is equivalent to approximately:


A) 10 to 20 cups.
B) 30 to 50 cups.
C) 100 cups.
D) There is no lethal dose.

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The mechanism of action of caffeine appears to be _____ receptotors.


A) stimulation of GABAA
B) blockade of GABAA
C) stimulation of adenosine
D) blockade of adenosine

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The majority of nicotine is metabolized in the:


A) plasma.
B) liver.
C) kidneys.
D) blood.

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The pharmacological effects of tobacco are due to ______; the disease states are due to _______.


A) nicotine; nicotine
B) tar; nicotine
C) tar; tar
D) nicotine; tar

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The half-life of caffeine may be shortened in:


A) inactive ingredients.
B) an active ingredient.
C) two active ingredients.
D) three active ingredients.

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