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Activation of C3a results in


A) increased blood vessel permeability.
B) cell lysis.
C) opsonization.
D) acute inflammation.
E) attraction of phagocytes.

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Histamine and kinins cause increased blood flow and capillary permeability.

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Complement proteins act as opsonins by binding to microorganisms and promoting phagocytosis.

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All of the following increase blood vessel permeability EXCEPT


A) lysozymes.
B) leukotrienes.
C) histamine.
D) kinins.
E) prostaglandins.

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Ingestion of certain lactic acid bacteria (LABs) has been shown to be beneficial for function and health of the intestinal tract.

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The lectin pathway for complement action is initiated by


A) mannose on host membranes.
B) gram- negative cell walls.
C) lectins of the microbe.
D) gram- positive cell walls.
E) mannose on the surface of microbes.

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Which of the following is found normally in serum?


A) interferon
B) complement
C) histamine
D) leukocytosis- promoting factor
E) TLRs

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All of the following occur during inflammation. What is the first step?


A) phagocyte migration
B) margination
C) diapedesis
D) vasodilation
E) repair

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Activation of C5-C9 results in


A) inflammation.
B) activation of C3.
C) lysis of microbial cells.
D) phagocytosis.
E) fixation of complement.

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Which of the following is involved in resistance to parasitic helminths?


A) monocytes
B) neutrophils
C) lymphocytes
D) eosinophils
E) basophils

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Each of the following provides protection from phagocytic digestion EXCEPT


A) leukocidins.
B) biofilms.
C) formation of phagolysosomes.
D) capsules.
E) M protein.

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All of the following protect the skin and mucous membranes from infection EXCEPT


A) HCl.
B) the "ciliary escalator."
C) tears.
D) saliva.
E) multiple layers of cells.

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Microorganisms that are members of the normal microbiota are also known to cause disease.

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Normal microbiota provide protection from infection in each of the following ways EXCEPT


A) they compete with pathogens for nutrients.
B) they produce lysozyme.
C) they make the chemical environment unsuitable for nonresident bacteria.
D) they produce antibacterial chemicals.
E) they change the pH of the environment.

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Which of the following exhibits the highest phagocytic activity?


A) macrophages
B) basophils
C) erythrocytes
D) eosinophils
E) neutrophils

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The dermis is composed of connective tissue and provides protection from the external environment.

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The classical pathway for complement activation is initiated by


A) factors released from damaged tissues.
B) antigen-antibody reactions.
C) factors released from phagocytes.
D) lipid- carbohydrate complexes and C3.
E) C5-C9.

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Which of the following is mismatched?


A) chemotaxis - chemical degradation inside a phagolysosome
B) scab - dried blood clot over injured tissue
C) pus - tissue debris and dead phagocytes in a white or yellow fluid
D) diapedesis - movement of leukocytes between capillary walls cells out of blood and into tissue
E) abcess - a cavity created by tissue damage and filled with pus

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A chill is a sign that


A) blood vessels are dilating.
B) body temperature is falling.
C) body temperature is not changing.
D) the metabolic rate is decreasing.
E) body temperature is rising.

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Macrophages arise from which of the following?


A) monocytes
B) eosinophils
C) basophils
D) neutrophils
E) lymphocytes

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