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What is the first step in the major events of the inflammation process?


A) Formation of pus and edema
B) Scar formation and/or resolution
C) Vascular reactions
D) Injury and mast cells releasing chemical mediators
E) Activation of the complement system

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All of the following pertain to interferon except it ________.


A) is a protein
B) is produced by certain white blood cells and tissue cells
C) includes alpha, beta, and gamma types
D) inhibits viruses, tumors, and cancer gene expression
E) increases capillary permeability and vasodilation

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If the patient's cilia are unable to clear his lungs of mucus, which line of host defense is breached?


A) First line of defense
B) Second line of defense
C) Third line of defense
D) First and second lines of defense

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Which type of white blood cells are particularly attracted to sites of parasitic worm infections?


A) Monocytes
B) Eosinophils
C) Basophils
D) Neutrophils
E) Lymphocytes

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Lysozyme is found in ________.


A) mucous membranes of the respiratory tract
B) mucous membranes of the gastrointestinal tract
C) salivary secretions
D) sweat from sweat glands
E) All of the choices are correct.

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Which line(s) of defense has been breached for this injury?


A) First line of defense
B) Second line of defense
C) First and second lines of defense
D) First, second and third lines of defense

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Histamine, serotonin, and bradykinin are all ________.


A) vasoactive mediators
B) mediators of B-cell activity
C) mediators of T-cell activity
D) mediators that increase chemotaxis
E) fever inducers

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The least numerous of all white blood cells that release histamine during inflammation and allergic reactions are ________.


A) basophils
B) eosinophils
C) neutrophils
D) monocytes
E) lymphocytes

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A

A low to moderate fever in an otherwise healthy person should be treated immediately with antipyretic drugs.

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What structures are found along lymphatic vessels and are heavily clustered in the armpit, groin, and neck?


A) Lymph nodes
B) Thymus
C) Spleen
D) GALT
E) Tonsils

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Each of the following are physical barriers to pathogens except ________.


A) unbroken skin
B) mucus
C) hairs
D) tears
E) T cells

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E

The four classic signs and symptoms of inflammation include all the following except ________.


A) redness
B) warmth
C) swelling
D) pain
E) chills

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The patient asks the nurse to explain what cilia are. All of the following statements are correct except ________.


A) cilia form a microscopic brush-like lining
B) cilia help move and expel foreign invaders
C) cilia compose a sort of microscopic "escalator" to expel invading organisms
D) cilia are chemical-excreting natural killer cells

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D

The nurse examines the child's tonsils while preparing to swab them with the culture swab. A white pustule coating is noted to be covering the tonsils. What is this pus composed of?


A) Waste from red blood cells
B) Live bacteria
C) Fibrin threads
D) White blood cells and debris from phagocytosis

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The human microbiome is considered an important component of the first line of defense. Which statement adequately reflects its role as a defensive barrier?


A) The human microbiota competes with pathogens for space and nutrients limiting their ability to cause infection, and trains the immune system to recognize antigens.
B) The organisms that comprise the microbiota are able to phagocytose potential pathogens, thereby eliminating them from the human host.
C) The human microbiome has evolved with the species so it is able to actively destroy pathogens by raising the body temperature when an infection by a pathogen occurs.
D) Cells in the human microbiome secrete cytokines that play a role in stimulating the immune response when a pathogen has entered the system.

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Plasma cells ________.


A) function in cell-mediated immunity
B) are derived from T lymphocytes
C) function in blood clotting
D) produce and secrete antibodies
E) All of the choices are correct.

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Inflammatory responses are orchestrated by the immune system and are part of the body's third line of defense.

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Cytokines are chemicals and proteins that are critical components of the immune system. Which of the following statements is incorrect regarding the function of cytokines?


A) All cytokines are synthesized to stimulate the inflammatory response; their purpose is to mediate vascular reactions and diapedesis.
B) Cytokines are secreted by a wide variety of cell types, including immune cells, epithelial and endothelial cells.
C) Cytokines play a role in both inflammatory stimulation, as well as being anti-inflammatory mediators.
D) Cytokines mediate communication between cells; they are crucial for stimulation, suppression and control of all aspects of the immune response.

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Which white blood cells comprise 20% to 30% of the circulating WBCs and are the cells that function in the body's third line of defense?


A) Basophils
B) Eosinophils
C) Neutrophils
D) Monocytes
E) Lymphocytes

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Which statement below characterizes the complement system?


A) Complement comprises a team of blood proteins that are activated in a cascade, ultimately leading to pathogen cytolysis, inflammation and enhanced phagocytosis.
B) Complement pyrogens stimulate the hypothalamus to raise the body temperature, increasing metabolism and preventing the growth of temperature-sensitive pathogens.
C) Complement proteins bind to cell surfaces and induce changes in genetic expression, eliminating not only pathogens, but cancer cells also.
D) Complement proteins, produced by a host cell in response to viral attack, are secreted and enter neighboring cells, stimulating the production of antiviral proteins in anticipation of an invasion.

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