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Assembly of new nucleosomes is carried out by complexes abbreviated_________ .


A) DSB
B) TLS
C) TERC
D) SSB
E) CAF

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E

Why are bacteria not dependent on telomerase for complete DNA replication?

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Telomerase allows for the accu...

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What is meant by a gene knockout?

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The designed loss of a specific gene in ...

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DNA polymerase III adds nucleotides_________ .


A) in the place of the primer RNA after it is removed
B) to internal sites in the DNA template
C) to the 5' end of the RNA primer
D) to the 3' end of the RNA primer
E) to both ends of the RNA primer

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The Meselson and Stahl's experiment provided conclusive evidence for the semiconservative replication of DNA in E.coli.What pattern of bands would occur in a CsCl gradient for conservative replication?

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After one generation in the 14N,there wo...

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Given the accompanying diagram,assume that a G1 chromosome left underwent one round of replication in 3H- thymidine and the metaphase chromosome right) had both chromatids labeled.Which of the following replicative models conservative,dispersive,semiconservative) could be eliminated by this observation? Given the accompanying diagram,assume that a G1 chromosome left underwent one round of replication in<sup> </sup><sup>3</sup>H- thymidine and the metaphase chromosome right) had both chromatids labeled.Which of the following replicative models conservative,dispersive,semiconservative) could be eliminated by this observation?   A) semiconservative B) dispersive C) conservative D) conservative and dispersive E) semiconservative and dispersive


A) semiconservative
B) dispersive
C) conservative
D) conservative and dispersive
E) semiconservative and dispersive

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A molecule that possesses both a protein component and an RNA component is referred to as a _________.


A) holoenzyme
B) ribonucleoprotein
C) polymerase
D) tetramer
E) dimer

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Chromatin is defined as_________ .


A) DNA complexed with protein
B) supercoiled loops of bacterial DNA
C) hybrid molecules of DNA and RNA
D) a catalytic molecule with a protein component and an RNA component
E) genetic material found only in mitochondria

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Describe two processes for which recombination is essential.

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The exchange of genetic information during meiosis,and the repair of double- stranded breaks in DNA molecules.

Explain why DNA primers can be used in in vitro DNA synthesis reactions,but not in vivo.

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The need for the primer is to provide a ...

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Explain the need for,and action of,DNA gyrase in bacterial DNA replication.

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DNA helicase induces supercoil...

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DNA replication in vivo requires a primer with a free 3' end.What molecular species provides this 3' end,and how is it provided?

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The free 3' end is provided by...

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After ONE round of DNA replication in Meselson and Stahl's classic experiment,_________.


A) the conservative model was conclusively proven to be an inaccurate model
B) both the conservative and the semiconservative models were still possibilities
C) the semiconservative model was conclusively proven to be the accurate model
D) the dispersive model was conclusively proven to be an inaccurate model
E) all three models of replication were still possibilities

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What is the name of the replication unit in prokaryotes,and how does it differ in eukaryotes?

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replicon; one replicon in prokaryotes,multiple replicons in eukaryotes

Which eukaryotic DNA polymerase would least likely be involved in repair?


A) fi
B) s
C) a
D) 6
E) y

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The process of making DNA from an RNA template is referred to as_________ .


A) transcription
B) transversion
C) recombination
D) reverse transcription
E) translation

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Telomerase reads _________ as a template and synthesizes _________as a product.


A) DNA; RNA
B) DNA; DNA
C) DNA; protein
D) RNA; RNA
E) RNA; DNA

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Describe the benefit to researchers of conditional mutants.

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Many mutations that would be interesting...

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Telomerase adds nucleotides to the_________ .


A) 5' end of the daughter strand
B) 5' end of the parental strand
C) 3' end of the parental strand
D) 3' end of the daughter strand

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Which of the following statement about DNA replication in E.coli is correct?


A) Single- stranded binding proteins are only required on the leading strand.
B) Only the lagging strand needs to be primed.
C) There are two molecules of DNA polymerase III per replication fork.
D) DNA polymerase I follows closely behind DNA helicase in the replication fork.
E) There are two molecules of DNA helicase per replication fork.

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