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Which of the following is associated with a greater predisposition for hypoglycemia due to decreased gluconeogenesis?


A) Pancreatitis
B) Cholecystitis
C) Cardiac failure
D) Renal failure

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A type II diabetic with a blood glucose of 24 mg/dL would most likely be unconscious due to:


A) insulin shock.
B) cerebral hypoglycemia.
C) gluconeogenesis.
D) diabetic ketoacidosis.

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Your diabetic patient asks you why diabetics need to take insulin. Which of the following answers is most accurate?


A) "Insulin helps glucose enter the cells of the body so it can be used for energy."
B) "Insulin helps the body eliminate excess glucose through the kidneys."
C) "Insulin breaks down glucose into proteins so it can be used by the cells for energy."
D) "Without insulin glucose is converted to ketone bodies, which are toxic in large quantities."

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Your patient is a 42-year-old male who had surgery four years ago to remove his posterior pituitary gland because of a tumor. He stopped taking replacement hormones because they caused depression. Which of the following is the most likely consequence of the patient's noncompliance with hormone replacement therapy?


A) Hypoglycemia
B) Hypertension
C) Reduced ability to fight infection
D) Dehydration

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Your patient is a 32-year-old female who is alert and sitting at her kitchen table complaining of dizziness and near-syncope with exertion. She describes a four-day history of a 104°F fever, nausea, vomiting, and diarrhea unrelieved with over-the-counter medications. Physical examination reveals dry skin and mucous membranes, lung sounds clear and equal bilaterally. HR = 131 and regular, BP = 84/60, RR = 20 and regular, SaO2 = 98%, blood glucose = 58 mg/dL. She has a history of colitis, for which she often takes prednisone, but she has been noncompliant with her prednisone therapy for the past five days because she cannot afford to refill her prescription. The treatment for this patient should include:


A) a one-liter NS bolus IV.
B) an IV of NS, 25 g dextrose IV, and 100 mg thiamine IV.
C) a one-liter NS bolus, IV, and 25 g dextrose IV.
D) 15 lpm oxygen by nonrebreather, IV of NS, 25 g dextrose.

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Hyperglycemia is most likely a result of damage to the pancreatic ________ cells.


A) alpha
B) beta
C) acinar
D) delta

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Secretion of glucagon from the pancreas results in ________, which causes a(n) ________ in blood glucose levels.


A) glucogenesis, decrease
B) glycogenolysis, decrease
C) glucogenesis, increase
D) glycogenolysis, increase

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Your patient is a 72-year-old male patient who is conscious but slow to respond to questions and commands. He has become increasingly lethargic, unemotional, and easily fatigued over the past two months. He has had a decreased appetite and has gained weight over the same period. The patient further states, "I'm constipated and always cold." Which of the following additional signs or symptoms would be consistent with this patient presentation?


A) A "moon-faced" appearance and hyperpigmentation of the skin
B) A puffy face, an enlarged tongue, and pale, doughy skin
C) Hypothermia, tachycardia, and hypertension
D) Goiter, atrial fibrillation, nausea, and vomiting

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Which of the following is the most reliable way to differentiate between a hyperglycemic emergency and a hypoglycemic emergency?


A) Determine whether or not the patient took his insulin or oral antihyperglycemic medicines.
B) Determine whether the patient is a type I or type II diabetic.
C) Follow the conventional wisdom, "Pale, cool, wet: low; red, hot, dry: high."
D) Assess the blood glucose level.

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Immediately after birth, an infant is allowed to suckle at the mother's breast. Palpation of the uterus suggests that the uterus is contracting. This finding can be attributed to:


A) secretion of oxytocin.
B) secretion of estrogen and progesterone.
C) inhibition of estrogen and progesterone.
D) inhibition of oxytocin.

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A three-year-old male patient has a history of an underdeveloped cell-mediated immune system. Which of the following most likely contribute to this deficiency?


A) Hypoadrenalism
B) HIV infection
C) Type I diabetes mellitus
D) Thymus gland insufficiency and a lack of thymosin secretion

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Which of the following best describes the relationship between the hypothalamus and the endocrine system?


A) The hypothalamus produces all of the releasing hormones that act on other endocrine organs.
B) The hypothalamus is the link between the central nervous system and the endocrine system.
C) The hypothalamus regulates most endocrine activities via positive feedback mechanisms.
D) The hypothalamus is also known as the posterior pituitary gland.

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Homeostasis refers to:


A) the tendency of the body to maintain an appropriate internal environment.
B) the body's ability to regulate the external environment.
C) intrinsic environmental regulatory factors.
D) extrinsic environmental regulatory factors.

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A 63-year-old female with a history of hypothyroidism presents in a stuporous state, responsive only to pain. Physical exam reveals thin hair, a puffy face, an enlarged tongue, and cold, doughy skin. Her heart rate is 70 and regular, RR is 10 and regular, BP is 90/62, blood glucose level is 60 mg/dL, and temperature is 86°F via a tympanic thermometer. Your treatment of this patient should NOT include:


A) active rewarming.
B) endotracheal intubation.
C) 50 percent dextrose, IV.
D) IV fluids at a TKO rate.

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Which of the following findings would be atypical in a patient with a history of Cushing's syndrome?


A) Blood glucose level of 190 mg/dL
B) Blood pressure of 154/86 mmHg
C) Bruising of the extremities
D) Temperature of 101°F

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A 16-year-old female with a history of diabetes is found unconscious in a high school bathroom following volleyball practice. She is tachycardic; has cool, clammy skin; is lethargic; is slightly combative; and is very confused. She is most likely experiencing:


A) hypoglycemia.
B) diabetic ketoacidosis.
C) hyperglycemia.
D) diabetic coma.

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Which of the following is least likely to result in hypoglycemia in a type I diabetic patient?


A) Increased exercise level
B) Taking insulin as usual but missing a meal
C) Eating foods high in sugar
D) Inadvertently administering too much insulin

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Acute exacerbation of Addison's disease can lead to ECG changes and cardiovascular collapse as a result of electrolyte imbalance secondary to:


A) increased mineralocorticoid secretion from the adrenal glands.
B) potassium retention and sodium excretion.
C) fluid retention, potassium excretion, and sodium retention.
D) decreased mineralocorticoid secretion with increased sodium and potassium excretion.

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Your patient is a 24-year-old male with a history of type I diabetes. You were called to his place of employment because he was behaving bizarrely. On your arrival he is confused and combative with a blood glucose level of 41 mg/dL. Due to poor vasculature and the patient's combativeness, you have not been able to start an IV. Which of the following is the best course of action?


A) Administer 1 mg glucagon, IM.
B) Administer 5 mg Valium, IM, and attempt the IV again when the patient is less agitated.
C) Administer half an amp (12.5 g) of 50 percent dextrose, IM.
D) Use four-point restraints to restrain the patient and transport. Attempt the IV again if the patient becomes unresponsive.

Correct Answer

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Which of the following is the most direct cause of polyuria in untreated diabetes?


A) Hyperglycemia
B) Hypoglycemia
C) Too much insulin
D) Too little insulin

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